Trimeric Spike Glycoprotein
Spike Glycoprotein Antibody |
|||
20-abx300551 | Abbexa |
|
|
Human IgG antibody Laboratories manufactures the trimeric spike glycoprotein reagents distributed by Genprice. The Trimeric Spike Glycoprotein reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact Spike Glycoprotein. Other Trimeric products are available in stock. Specificity: Trimeric Category: Spike Group: Glycoprotein
Spike Glycoprotein Polyclonal Antibody, HRP Conjugated |
||
EpiGentek |
|
|
Spike Glycoprotein Polyclonal Antibody, FITC Conjugated |
||
EpiGentek |
|
|
Spike Glycoprotein Polyclonal Antibody, Biotin Conjugated |
||
EpiGentek |
|
|
Spike Glycoprotein Polyclonal Antibody, HRP Conjugated |
||
EpiGentek |
|
|
Spike Glycoprotein Polyclonal Antibody, FITC Conjugated |
||
EpiGentek |
|
|
Spike Glycoprotein Polyclonal Antibody, Biotin Conjugated |
||
EpiGentek |
|
|
Human coronavirus OC43 Spike glycoprotein (S) |
||
Cusabio |
|
|
Description: Recombinant Human coronavirus OC43 Spike glycoprotein(S) ,partial expressed in E.coli |
Recombinant Novel Coronavirus Spike Glycoprotein(S), Partial |
|||
E80018 | EpiGentek |
|
|
Infectious bronchitis virus Spike glycoprotein S1 subunit (S1) |
|||
1-CSB-RP182154v | Cusabio |
|
|
Description: Recombinant Infectious bronchitis virus Spike glycoprotein S1 subunit(S1),partial expressed in E.coli |
Recombinant Human Spike glycoprotein Protein, His, Yeast-1mg |
|||
QP7178-ye-1mg | EnQuireBio | 1mg | EUR 2262 |
Recombinant Human Spike glycoprotein Protein, His, Yeast-10ug |
|||
QP7178-ye-10ug | EnQuireBio | 10ug | EUR 283.2 |
Recombinant Human Spike glycoprotein Protein, His, Yeast-50ug |
|||
QP7178-ye-50ug | EnQuireBio | 50ug | EUR 358.8 |
Recombinant Human Spike glycoprotein Protein, His, Yeast-100ug |
|||
QP7178-ye-100ug | EnQuireBio | 100ug | EUR 576 |
Recombinant Human Spike glycoprotein Protein, His, Yeast-200ug |
|||
QP7178-ye-200ug | EnQuireBio | 200ug | EUR 892.8 |
Recombinant Human Spike glycoprotein Protein, His, Yeast-500ug |
|||
QP7178-ye-500ug | EnQuireBio | 500ug | EUR 1447.2 |
Recombinant SARS-CoV-2 Spike Glycoprotein(S) (D614G), Partial |
|||
E80028 | EpiGentek |
|
|
Recombinant Human CoVs spike glycoprotein Protein (aa 1-760) [His] |
|||
VAng-Wyb7328-100g | Creative Biolabs | 100 µg | EUR 3249.6 |
Description: Human coronavirus (isolate HKU1) spike glycoprotein, recombinant protein. |
Recombinant Human CoVs spike glycoprotein Protein (aa 1-760) [His] |
|||
VAng-Wyb7328-20g | Creative Biolabs | 20 µg | EUR 1198.8 |
Description: Human coronavirus (isolate HKU1) spike glycoprotein, recombinant protein. |
Recombinant Human CoVs spike glycoprotein Protein (aa 1-760) [His] |
|||
VAng-Wyb7328-50g | Creative Biolabs | 50 µg | EUR 2096.4 |
Description: Human coronavirus (isolate HKU1) spike glycoprotein, recombinant protein. |
Recombinant Human Spike glycoprotein Protein, His-SUMO, E.coli-10ug |
|||
QP7178-ec-10ug | EnQuireBio | 10ug | EUR 240 |
Recombinant Human Spike glycoprotein Protein, His-SUMO, E.coli-1mg |
|||
QP7178-ec-1mg | EnQuireBio | 1mg | EUR 1958.4 |
Recombinant Human Spike glycoprotein Protein, His-SUMO, E.coli-50ug |
|||
QP7178-ec-50ug | EnQuireBio | 50ug | EUR 315.6 |
SARS-CoV-2 (COVID-19) Trimeric Spike (S) Recombinant Protein |
|||
10-075 | ProSci | 0.1 mg | EUR 991.5 |
Description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is an enveloped, single-stranded, positive-sense RNA virus that belongs to the Coronaviridae family 1. The SARS-CoV-2 genome, which shares 79.6% identity with SARS-CoV, encodes four essential structural proteins: the spike (S), envelope (E), membrane (M), and nucleocapsid protein (N) 2. The S protein is a transmembrane, homotrimeric, class I fusion glycoprotein that mediates viral attachment, fusion, and entry into host cells 3. Each ~180 kDa monomer contains two functional subunits, S1 (~700 a.a) and S2 (~600 a.a), that mediate viral attachment and membrane fusion, respectively. S1 contains two major domains, the N-terminal (NTD) and C-terminal domains (CTD). The CTD contains the receptor-binding domain (RBD), which binds to the angiotensin-converting enzyme 2 (ACE2) receptor on host cells 3-5. Although both SARS-CoV and SARS-CoV-2 bind the ACE2 receptor, the RBDs only share ~73% amino acid identity, and the SARS-CoV-2 RBD binds with a higher affinity compared to SARS-CoV 3, 6. The RBD is dynamic and undergoes hinge-like conformational changes, referred to as the “down” or “up” conformations, which hide or expose the receptor-binding motifs, respectively 7. Following receptor binding, S1 destabilizes, and TMPRSS2 cleaves S2, which undergoes a pre- to post-fusion conformation transition, allowing for membrane fusion 8, 9. The S protein has been the main focus of therapeutic and vaccine design as it is highly immunogenic. Both neutralizing antibodies 10,11 and memory T cells 12,13 targeting the S protein are present in the sera of convalescent COVID-19 patients. |
Recombinant Human Spike glycoprotein Protein, His-SUMO, E.coli-100ug |
|||
QP7178-ec-100ug | EnQuireBio | 100ug | EUR 489.6 |