Immune evasion is a vital most cancers hallmark and the understanding of its mechanisms has generated profitable therapeutic approaches. Induction of immunogenic cell demise (ICD) is anticipated to draw immune cell populations that promote innate and adaptive immune responses. Right here, we current a important advance for our adenovirus-mediated gene remedy method, the place the mixed p14ARF and human interferon-β (IFNβ) gene switch to human melanoma cells led to oncolysis, ICD and subsequent activation of immune cells. Our outcomes point out that IFNβ alone or together with p14ARF was capable of induce large cell demise within the human melanoma cell line SK-MEL-147, although caspase 3/7 activation was not important.
In situ gene remedy of s.c. SK-MEL-147 tumors in Nod-Scid mice revealed inhibition of tumor development and elevated survival in response to IFNβ alone or together with p14ARF. Emission of important markers of ICD (exposition of calreticulin, secretion of ATP and IFNβ) was stronger when cells had been handled with mixed p14ARF and IFNβ gene switch. Co-culture of beforehand transduced SK-MEL-147 cells with monocyte-derived dendritic cells (Mo-DCs) derived from wholesome donors resulted in elevated ranges of activation markers HLA-DR, CD80, and CD86.
Activated Mo-DCs had been capable of prime autologous and allogeneic T cells, leading to elevated secretion of IFNγ, TNF-α, and IL-10. Preliminary knowledge confirmed that T cells primed by Mo-DCs activated with p14ARF+IFNβ-transduced SK-MEL-147 cells had been capable of induce the lack of viability of contemporary non-transduced SK-MEL-147 cells, suggesting the induction of a particular cytotoxic inhabitants that acknowledged and killed SK-MEL-147 cells. Collectively, our outcomes point out that p14ARF and IFNβ delivered by our adenoviral system induced oncolysis in human melanoma cells accompanied by adaptive immune response activation and regulation.
LT-Okay63 Enhances B Cell Activation and Survival Elements in Neonatal Mice That Interprets Into Lengthy-Lived Humoral Immunity
Adjuvants improve magnitude and length of immune responses induced by vaccines. On this research we assessed in neonatal mice if and the way the adjuvant LT-Okay63 given with a pneumococcal conjugate vaccine, Pnc1-TT, may have an effect on the expression of tumor necrosis issue receptor (TNF-R) superfamily members, identified to be concerned within the initiation and upkeep of antibody responses; B cell activating issue receptor (BAFF-R) and B cell maturation antigen (BCMA) and their ligands, BAFF, and a proliferation inducing ligand (APRIL). Initially we assessed the maturation standing of various B cell populations and their expression of BAFF-R and BCMA. Neonatal mice had dramatically fewer B cells than grownup mice and the composition of various subsets throughout the B cell pool differed tremendously.
Proportionally newly fashioned B cells had been most considerable, however they’d diminished BAFF-R expression which may clarify low proportions of marginal zone and follicular B cells noticed. Restricted BCMA expression was additionally detected in neonatal pre-plasmablasts/plasmablasts. LT-Okay63 enhanced vaccine-induced BAFF-R expression in splenic marginal zone, follicular and newly fashioned B cells, resulting in elevated plasmablast/plasma cells, and their enhanced expression of BCMA in spleen and bone marrow. Moreover, the induction of BAFF and APRIL expression occurred early in neonatal mice immunized with Pnc1-TT both with or with out LT-Okay63. Nonetheless, BAFF+ and APRIL+ cells in spleens had been maintained at a better degree in mice that obtained the adjuvant. Moreover, the early improve of APRIL+ cells in bone marrow was extra profound in mice immunized with vaccine and adjuvant.
Lastly, we assessed, for the primary time in neonatal mice, accent cells of the plasma cell area of interest in bone marrow and their secretion of APRIL. We discovered that LT-Okay63 enhanced the frequency and APRIL expression of eosinophils, macrophages, and megakaryocytes, which probably contributed to plasma cell survival, regardless that APRIL+ cells confirmed a quick decline. All this was related to enhanced, sustained vaccine-specific antibody-secreting cells in bone marrow and persisting vaccine-specific serum antibodies. Our research sheds mild on the mechanisms behind the adjuvanticity of LT-Okay63 and identifies molecular pathways that must be triggered by vaccine adjuvants to induce sustained humoral immunity in formative years.
Combined p14ARF and Interferon-β Gene Transfer to the Human Melanoma Cell Line SK-MEL-147 Promotes Oncolysis and Immune Activation
Leishmania amazonensis Promastigotes or Extracellular Vesicles Modulate B-1 Cell Activation and Differentiation
B-1 cells are thought-about an innate-like B cell inhabitants that participates in efficient innate and adaptive responses to pathogens. B-1 cells produce immunoglobulins, cytokines, chemokines, migrate to inflammatory websites, and differentiate into mononuclear phagocyte-like cells. Murine B-1 cells phagocytosed Leishmania in vitro and in vivo and take part in immunity in opposition to Leishmania. Our group confirmed that B-1 cells or their extracellular vesicles (EVs) led to a resistance to experimental an infection by L. amazonensis. Nonetheless, the B-1 cells’ responses to Leishmania or EVs remoted from parasites are nonetheless poorly characterised. Learning the activation and differentiation of B-1 cells in vivo can contribute to a greater understanding of how these cells take part in immunity to L. amazonensis.
Thus, we evaluated the expression of myeloid (M-csfr, G-csfr, Spi-1) and lymphoid (EBF, E2A, IL-7R) lineage dedication components, Toll-like receptors (TLRs), activation cell floor markers, nitric oxide (NO) and reactive oxygen species (ROS) manufacturing in murine peritoneal B-1 cells collected after 24 or 48 h post-infection with Leishmania (Leishmania) amazonensis promastigotes or EVs launched by the parasites. Our outcomes demonstrated that L. amazonensis an infection didn’t stimulate the expression of CD40, CD80, CD86, F4/80, and MHC II in B-1 cells, however a major lower within the manufacturing of NO and ROS was noticed.
Casein Kappa (CSN3) Antibody |
20-abx171599 |
Abbexa |
-
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|
|
|
Casein Kappa (CSN3) Antibody |
20-abx171600 |
Abbexa |
-
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-
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|
|
|
Casein Kappa (CSN3) Antibody |
abx129181-100l |
Abbexa |
100 µl |
EUR 275 |
Casein Kappa (CSN3) Antibody |
abx129181-1ml |
Abbexa |
1 ml |
EUR 750 |
Casein Kappa (CSN3) Antibody |
abx129181-200l |
Abbexa |
200 µl |
EUR 337.5 |
Casein Kappa (CSN3) Antibody |
abx130922-100l |
Abbexa |
100 µl |
EUR 887.5 |
Casein Kappa (CSN3) Antibody |
abx130922-20l |
Abbexa |
20 µl |
EUR 300 |
Casein Kappa (CSN3) Antibody |
abx130922-50l |
Abbexa |
50 µl |
EUR 387.5 |
Kappa Casein (CSN3) Antibody |
abx232019-100ug |
Abbexa |
100 ug |
EUR 577.2 |
|
Kappa Casein (CSN3) Antibody |
abx232019-100g |
Abbexa |
100 µg |
EUR 350 |
Recombinant Casein Kappa (CSN3) |
RPJ331Bo01 |
Cloud-Clone |
10ug |
EUR 208 |
Recombinant Casein Kappa (CSN3) |
4-RPJ331Bo01 |
Cloud-Clone |
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|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Bovine Casein Kappa expressed in: E.coli |
Recombinant Casein Kappa (CSN3) |
RPJ331Hu01 |
Cloud-Clone |
10ug |
EUR 176 |
Recombinant Casein Kappa (CSN3) |
4-RPJ331Hu01 |
Cloud-Clone |
-
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|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Casein Kappa expressed in: E.coli |
Human Casein Kappa ELISA Kit |
IHUCSN3KT |
Innovative research |
each |
EUR 733 |
|
Description: Human Casein Kappa ELISA Kit |
Cow Casein Kappa (CSN3) Protein |
20-abx650845 |
Abbexa |
-
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|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Bovine Casein Kappa ELISA Kit |
IBOCSN3KT |
Innovative research |
each |
EUR 866 |
|
Description: Bovine Casein Kappa ELISA Kit |
Cow Casein Kappa (CSN3) Protein |
abx650845-5mg |
Abbexa |
5 mg |
EUR 662.5 |
Human Casein Kappa (CSN3) Protein |
20-abx167038 |
Abbexa |
-
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|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Human Casein Kappa (CSN3) Protein |
abx167038-100g |
Abbexa |
100 µg |
EUR 575 |
Human Casein Kappa (CSN3) Protein |
abx167038-10g |
Abbexa |
10 µg |
EUR 225 |
Human Casein Kappa (CSN3) Protein |
abx167038-50g |
Abbexa |
50 µg |
EUR 400 |
Polyclonal Antibody to Casein Kappa (CSN3) |
PAJ331Bo01 |
Cloud-Clone |
100ul |
EUR 291 |
|
Polyclonal Antibody to Casein Kappa (CSN3) |
PAJ331Hu01 |
Cloud-Clone |
100ul |
EUR 245 |
|
Cow Casein kappa (CSN3) CLIA Kit |
20-abx495684 |
Abbexa |
-
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-
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-
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|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Cow Casein kappa (CSN3) ELISA Kit |
20-abx150084 |
Abbexa |
-
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-
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-
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|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
ELISA Kit for Casein Kappa (CSN3) |
SEJ331Bo |
Cloud-Clone |
96Т |
EUR 840 |
|
ELISA Kit for Casein Kappa (CSN3) |
SEJ331Hu |
Cloud-Clone |
96Т |
EUR 700 |
|
Casein Kappa (CSN3) Polyclonal Antibody (Human) |
4-PAJ331Hu01 |
Cloud-Clone |
-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Casein Kappa (CSN3) |
Human Casein kappa (CSN3) CLIA Kit |
20-abx495685 |
Abbexa |
-
Ask for price
-
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-
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|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Casein Kappa (CSN3) Polyclonal Antibody (Bovine) |
4-PAJ331Bo01 |
Cloud-Clone |
-
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-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Bovine Casein Kappa (CSN3) |
Human Casein Kappa (CSN3)ELISA Kit |
201-12-2883 |
SunredBio |
96 tests |
EUR 528 |
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Human Casein Kappa (CSN3) ELISA Kit |
DLR-CSN3-Hu |
DL Develop |
96T |
EUR 463 |
|
Description: serum, plasma or other biological fluids. |
Human Casein Kappa (CSN3) ELISA Kit |
DLR-CSN3-Hu-48T |
DL Develop |
48T |
EUR 620.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Casein Kappa (CSN3) in samples from serum, plasma or other biological fluids. |
Human Casein Kappa (CSN3) ELISA Kit |
DLR-CSN3-Hu-96T |
DL Develop |
96T |
EUR 807.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Casein Kappa (CSN3) in samples from serum, plasma or other biological fluids. |
Human CSN3(Casein Kappa) ELISA Kit |
ELK4819-48T |
ELK Biotech |
48T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CSN3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CSN3. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human CSN3, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human CSN3 in the samples is then determined by comparing the OD of the samples to the standard curve. |
Human CSN3(Casein Kappa) ELISA Kit |
ELK4819-96T |
ELK Biotech |
96T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CSN3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CSN3. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human CSN3, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human CSN3 in the samples is then determined by comparing the OD of the samples to the standard curve. |
Human Casein Kappa (CSN3) ELISA Kit |
DL-CSN3-Hu |
DL Develop |
96T |
EUR 441 |
|
Description: serum, plasma or other biological fluids. |
Human Casein Kappa (CSN3) ELISA Kit |
EK13477 |
SAB |
96Т |
EUR 768 |
|
Human Casein kappa (CSN3) ELISA Kit |
20-abx150942 |
Abbexa |
-
Ask for price
-
Ask for price
-
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|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
Human Casein Kappa (CSN3) ELISA Kit |
RDR-CSN3-Hu-48T |
Reddot Biotech |
48T |
EUR 475.34 |
|
Description: serum, plasma and other biological fluids. |
Human Casein Kappa (CSN3) ELISA Kit |
RDR-CSN3-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 652.8 |
Human Casein Kappa (CSN3) ELISA Kit |
RDR-CSN3-Hu-96T |
Reddot Biotech |
96T |
EUR 679.04 |
|
Description: serum, plasma and other biological fluids. |
Human Casein Kappa (CSN3) ELISA Kit |
RDR-CSN3-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 907.2 |
Human Casein Kappa (CSN3) ELISA Kit |
RD-CSN3-Hu-48T |
Reddot Biotech |
48T |
EUR 452.7 |
|
Description: serum, plasma and other biological fluids. |
Human Casein Kappa (CSN3) ELISA Kit |
RD-CSN3-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 625.2 |
Human Casein Kappa (CSN3) ELISA Kit |
RD-CSN3-Hu-96T |
Reddot Biotech |
96T |
EUR 646.7 |
|
Description: serum, plasma and other biological fluids. |
Human Casein Kappa (CSN3) ELISA Kit |
RD-CSN3-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 867.6 |
Human Casein Kappa ELISA Kit (CSN3) |
RK01196 |
Abclonal |
96 Tests |
EUR 625.2 |
Human Casein Kappa (CSN3) ELISA Kit |
SEJ331Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5677.8 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Casein Kappa (CSN3) in Breast milk and other biological fluids. |
Human Casein Kappa (CSN3) ELISA Kit |
SEJ331Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 572.76 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Casein Kappa (CSN3) in Breast milk and other biological fluids. |
Human Casein Kappa (CSN3) ELISA Kit |
SEJ331Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 766.8 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Casein Kappa (CSN3) in Breast milk and other biological fluids. |
Human Casein Kappa (CSN3) ELISA Kit |
SEJ331Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 3090.6 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Casein Kappa (CSN3) in Breast milk and other biological fluids. |
Human Casein Kappa (CSN3) ELISA Kit |
4-SEJ331Hu |
Cloud-Clone |
-
Ask for price
-
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-
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|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Casein Kappa (CSN3) in samples from Breast milk and other biological fluids with no significant corss-reactivity with analogues from other species. |
Bovine Casein Kappa (CSN3) ELISA Kit |
DLR-CSN3-b |
DL Develop |
96T |
EUR 547 |
|
Description: milk. |
Bovine Casein Kappa (CSN3) ELISA Kit |
DLR-CSN3-b-48T |
DL Develop |
48T |
EUR 710.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Casein Kappa (CSN3) in samples from milk. |
Bovine Casein Kappa (CSN3) ELISA Kit |
DLR-CSN3-b-96T |
DL Develop |
96T |
EUR 932.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Casein Kappa (CSN3) in samples from milk. |
Cattle CSN3(Casein Kappa) ELISA Kit |
ELK8007-48T |
ELK Biotech |
48T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Cattle CSN3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Cattle CSN3. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Cattle CSN3, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Cattle CSN3 in the samples is then determined by comparing the OD of the samples to the standard curve. |
Cattle CSN3(Casein Kappa) ELISA Kit |
ELK8007-96T |
ELK Biotech |
96T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Cattle CSN3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Cattle CSN3. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Cattle CSN3, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Cattle CSN3 in the samples is then determined by comparing the OD of the samples to the standard curve. |
Bovine Casein Kappa (CSN3) ELISA Kit |
DL-CSN3-b |
DL Develop |
96T |
EUR 521 |
|
Description: milk. |
Bovine Casein Kappa (CSN3) ELISA Kit |
EK13476 |
SAB |
96Т |
EUR 768 |
|
Bovine Casein Kappa (CSN3) ELISA Kit |
RDR-CSN3-b-48T |
Reddot Biotech |
48T |
EUR 561.02 |
|
Description: milk. |
Bovine Casein Kappa (CSN3) ELISA Kit |
RDR-CSN3-b-48Tests |
Reddot Biotech |
48 Tests |
EUR 759.6 |
Bovine Casein Kappa (CSN3) ELISA Kit |
RDR-CSN3-b-96T |
Reddot Biotech |
96T |
EUR 801.47 |
|
Description: milk. |
Bovine Casein Kappa (CSN3) ELISA Kit |
RDR-CSN3-b-96Tests |
Reddot Biotech |
96 Tests |
EUR 1060.8 |
Bovine Casein Kappa (CSN3) ELISA Kit |
RD-CSN3-b-48T |
Reddot Biotech |
48T |
EUR 534.3 |
|
Description: milk. |
Bovine Casein Kappa (CSN3) ELISA Kit |
RD-CSN3-b-48Tests |
Reddot Biotech |
48 Tests |
EUR 727.2 |
Bovine Casein Kappa (CSN3) ELISA Kit |
RD-CSN3-b-96T |
Reddot Biotech |
96T |
EUR 763.3 |
|
Description: milk. |
Bovine Casein Kappa (CSN3) ELISA Kit |
RD-CSN3-b-96Tests |
Reddot Biotech |
96 Tests |
EUR 1012.8 |
Bovine Casein Kappa ELISA Kit (CSN3) |
RK00450 |
Abclonal |
96 Tests |
EUR 687.6 |
Bovine Casein Kappa (CSN3) ELISA Kit |
SL0215Bo |
Sunlong |
- |
Ask for price |
|
Cattle Casein Kappa (CSN3) ELISA Kit |
SEJ331Bo-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 6777.36 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Cattle Casein Kappa (CSN3) in milk. |
Cattle Casein Kappa (CSN3) ELISA Kit |
SEJ331Bo-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 663.31 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Cattle Casein Kappa (CSN3) in milk. |
Cattle Casein Kappa (CSN3) ELISA Kit |
SEJ331Bo-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 896.16 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Cattle Casein Kappa (CSN3) in milk. |
Cattle Casein Kappa (CSN3) ELISA Kit |
SEJ331Bo-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 3672.72 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Cattle Casein Kappa (CSN3) in milk. |
Cattle Casein Kappa (CSN3) ELISA Kit |
4-SEJ331Bo |
Cloud-Clone |
-
Ask for price
-
Ask for price
-
Ask for price
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Cattle Casein Kappa (CSN3) in samples from milk with no significant corss-reactivity with analogues from other species. |
Human Casein Kappa, CSN3 GENLISA ELISA |
KBH2882 |
Krishgen |
1 x 96 wells |
EUR 286 |
Casein Kappa (CSN3) Polyclonal Antibody (Human), PE |
4-PAJ331Hu01-PE |
Cloud-Clone |
-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Casein Kappa (CSN3). This antibody is labeled with PE. |
Casein Kappa (CSN3) Polyclonal Antibody (Bovine), PE |
4-PAJ331Bo01-PE |
Cloud-Clone |
-
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-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Bovine Casein Kappa (CSN3). This antibody is labeled with PE. |
Casein Kappa (CSN3) Polyclonal Antibody (Human), APC |
4-PAJ331Hu01-APC |
Cloud-Clone |
-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Casein Kappa (CSN3). This antibody is labeled with APC. |
Casein Kappa (CSN3) Polyclonal Antibody (Human), Cy3 |
4-PAJ331Hu01-Cy3 |
Cloud-Clone |
-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Casein Kappa (CSN3). This antibody is labeled with Cy3. |
Casein Kappa (CSN3) Polyclonal Antibody (Human), HRP |
4-PAJ331Hu01-HRP |
Cloud-Clone |
-
Ask for price
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-
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-
Ask for price
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Casein Kappa (CSN3). This antibody is labeled with HRP. |
Casein Kappa (CSN3) Polyclonal Antibody (Bovine), APC |
4-PAJ331Bo01-APC |
Cloud-Clone |
-
Ask for price
-
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-
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-
Ask for price
-
Ask for price
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
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Description: A Rabbit polyclonal antibody against Bovine Casein Kappa (CSN3). This antibody is labeled with APC. |
Casein Kappa (CSN3) Polyclonal Antibody (Bovine), Cy3 |
4-PAJ331Bo01-Cy3 |
Cloud-Clone |
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- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
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Description: A Rabbit polyclonal antibody against Bovine Casein Kappa (CSN3). This antibody is labeled with Cy3. |
Casein Kappa (CSN3) Polyclonal Antibody (Bovine), HRP |
4-PAJ331Bo01-HRP |
Cloud-Clone |
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- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
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Description: A Rabbit polyclonal antibody against Bovine Casein Kappa (CSN3). This antibody is labeled with HRP. |
Casein Kappa (CSN3) Polyclonal Antibody (Human), FITC |
4-PAJ331Hu01-FITC |
Cloud-Clone |
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- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
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Description: A Rabbit polyclonal antibody against Human Casein Kappa (CSN3). This antibody is labeled with FITC. |
ELISA kit for Human CSN3 (Casein Kappa) |
ELK4819 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
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Description: A sandwich ELISA kit for detection of Casein Kappa from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Casein Kappa (CSN3) Polyclonal Antibody (Bovine), FITC |
4-PAJ331Bo01-FITC |
Cloud-Clone |
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
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Description: A Rabbit polyclonal antibody against Bovine Casein Kappa (CSN3). This antibody is labeled with FITC. |
Rat Kappa casein(CSN3) ELISA kit |
E01A14264 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Rat Kappa casein(CSN3) ELISA kit |
E02K0085-192T |
BlueGene |
192 tests |
EUR 1524 |
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Description: A sandwich ELISA for quantitative measurement of Rat Kappa casein(CSN3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Kappa casein(CSN3) ELISA kit |
E02K0085-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
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Description: A sandwich ELISA for quantitative measurement of Rat Kappa casein(CSN3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Kappa casein(CSN3) ELISA kit |
E02K0085-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
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Description: A sandwich ELISA for quantitative measurement of Rat Kappa casein(CSN3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
The an infection induced a considerably larger arginase expression in B-1 cells, however the stimulation with EVs led to a lower on this gene expression. TLR-2 and TLR-6 had considerably larger expression in B-1 cells from mice intraperitoneally stimulated with the parasite. The TLR-9 expression was larger in animals contaminated or stimulated for 48 h with EVs. Apparently, in B-1 cells the stimulus with L. amazonensis led to a considerable improve within the expression of myeloid restricted transcription components. Thus, our research means that the parasites or EVs in another way modulated the activation and differentiation of B-1 cells.