Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis

Autoreactive B cells mediate autoimmune pathology, however precisely how stays unknown. A trademark of rheumatoid arthritis (RA), a standard autoimmune illness, is the presence of disease-specific anticitrullinated protein antibodies (ACPAs). Right here, we confirmed that ACPA-positive B cells in sufferers with RA strongly expressed T cell-stimulating ligands, produced considerable proinflammatory cytokines, and have been proliferative whereas escaping inhibitory alerts.

This activated state was discovered at totally different levels in numerous levels of illness: highest in sufferers with recent-onset RA, reasonable in sufferers with established RA, and much much less pronounced in ACPA-positive people “in danger” for growing illness. The activated autoreactive B cell response persevered in sufferers who achieved medical remission with standard remedy. ACPA-positive B cells in blood and synovial fluid secreted elevated quantities of the chemoattractant interleukin-8, which attracted neutrophils, probably the most considerable immune cell in arthritic joints.

Tetanus toxoid-specific B cells from the identical sufferers exhibited properties of reminiscence B cells with out the activation and proliferation phenotype, however these cells transiently acquired an analogous proliferative phenotype upon booster vaccination. Collectively, these knowledge indicated that steady antigenic triggering of autoreactive B cells happens in human autoimmune illness and assist the rising idea of immunological exercise that persists beneath remedy even in medical remission, which can revise our present idea of remedy targets for future therapeutic interventions. As well as, our knowledge pointed to a pathogenic position of ACPA-positive B cells within the inflammatory illness course of underlying RA and favor approaches that intention at their antigen-specific inactivation or depletion.

 

Destiny Mapping Quantifies the Dynamics of B Cell Growth and Activation all through Life

Follicular mature (FM) and germinal middle (GC) B cells underpin humoral immunity, however the dynamics of their era and upkeep should not clearly outlined. Right here, we exploited a fate-mapping system in mice that tracks B cells as they grow to be peripheral subsets, along with a cell division destiny reporter mouse and mathematical fashions. We discover that FM cells are kinetically homogeneous, recirculate freely, are regularly replenished from transitional populations, and self-renew not often.
In distinction, GC B cell lineages persist for weeks with fast turnover and site-specific dynamics. These within the spleen derive from transitional cells and are kinetically homogeneous, whereas these in lymph nodes derive from FM B cells and comprise each transient and protracted clones. These variations probably derive from the character of antigen publicity on the totally different websites. Our integrative method additionally reveals how the host setting drives cell-extrinsic, age-related adjustments in B cell homeostasis. Lack of practical β-cell mass is a trademark of Kind 1 and Kind 2 Diabetes.
Macrophages play an integral position within the upkeep or destruction of pancreatic β-cells. The impact of the macrophage β-cell interplay depends on the activation state of the macrophage. Macrophages will be activated throughout a spectrum, from pro-inflammatory to anti-inflammatory and tissue transforming. The components secreted by these differentially activated macrophages and their impact on β-cells outline the impact on practical β-cell mass. On this evaluate, the spectrum of macrophage activation is mentioned, as are the optimistic and destructive results on β-cell survival, enlargement, and performance in addition to the outlined components launched from macrophages that impinge on practical β-cell mass.
 Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis

Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis

Zika Virus NS2A and NS4A Downregulate the Promoter Exercise of Nuclear Issue Kappa-Gentle-Chain-Enhancer of Activated B Cells

Since ZIKV was first detected at Uganda in 1947 and, critical outbreaks have globally occurred within the Yap Island, the French Polynesia and Brazil. Despite the fact that the variety of an infection and unfold of ZIKV have sharply rise, the pathogenesis or replication mechanisms ZIKV haven’t been effectively studied. Zika virus (ZIKV) is just lately highlighted Flavivirus, a mosquito born rising virus inflicting microcephaly and the Guillain-Barre syndrome in fetuses and adults, respectively. ZIKV polyprotein consists of three structural proteins named C, prM and E and 7 nonstructural proteins named NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5 in 11-kb single-stranded optimistic sense RNA genome.
The operate of particular person ZIKV genes on the host innate immune responses have been barely studied. On this research, we investigated the modulations of the NF-κB promoter exercise associated by the MDA5/RIG-I signaling pathway. Within the outcomes, two nonstructural proteins, NS2A and NS4A, dramatically suppressed the NF-κB promoter exercise by inhibiting signaling components on MDA5/RIG-I signaling pathway associated to activation of NF-κB. Curiously, NS2A suppressed all parts of MDA5/RIG-I signaling pathway, however NS4A inhibited most signaling molecules, besides IKKε and IRF3-5D. As well as, each NS2A and NS4A down-regulated MDA5 associated NF-κB promoter exercise in dose-dependent method.

Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody

20-abx128602
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Receptor Activator Of Nuclear Factor Kappa B (RANk) Antibody

20-abx174339
  • EUR 410.40
  • EUR 1028.40
  • EUR 526.80
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Active Receptor Activator Of Nuclear Factor Kappa B (RANk)

4-APC057Hu01
  • EUR 932.86
  • EUR 373.20
  • EUR 3168.19
  • EUR 1136.06
  • EUR 2152.13
  • EUR 699.60
  • EUR 7740.48
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Receptor Activator Of Nuclear Factor Kappa B expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk)

4-RPC057Hu01
  • EUR 571.58
  • EUR 276.00
  • EUR 1813.44
  • EUR 684.48
  • EUR 1248.96
  • EUR 458.40
  • EUR 4353.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Receptor Activator Of Nuclear Factor Kappa B expressed in: E.coli

Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk)

4-RPC057Mu01
  • EUR 593.09
  • EUR 282.00
  • EUR 1894.08
  • EUR 711.36
  • EUR 1302.72
  • EUR 472.80
  • EUR 4555.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Receptor Activator Of Nuclear Factor Kappa B expressed in: E.coli

Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk)

4-RPC057Ra01
  • EUR 614.59
  • EUR 288.00
  • EUR 1974.72
  • EUR 738.24
  • EUR 1356.48
  • EUR 487.20
  • EUR 4756.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Receptor Activator Of Nuclear Factor Kappa B expressed in: E.coli

Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody

20-abx270117
  • EUR 594.00
  • EUR 693.60
  • EUR 343.20
  • EUR 1062.00
  • EUR 444.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody

20-abx270227
  • EUR 594.00
  • EUR 693.60
  • EUR 343.20
  • EUR 1062.00
  • EUR 444.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator Of Nuclear Factor Kappa B (RANk) Antibody

20-abx174340
  • EUR 1095.60
  • EUR 560.40
  • 1 mg
  • 200 ug

Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) Protein

20-abx168512
  • EUR 861.60
  • EUR 343.20
  • EUR 2665.20
  • EUR 1028.40
  • EUR 610.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) Protein

20-abx166643
  • EUR 794.40
  • EUR 326.40
  • EUR 2448.00
  • EUR 944.40
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx104600
  • EUR 477.60
  • EUR 159.60
  • EUR 1328.40
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Receptor Activator Of Nuclear Factor Kappa B (RANk) Protein

20-abx068826
  • EUR 828.00
  • EUR 343.20
  • EUR 2548.80
  • EUR 978.00
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx130179
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx131777
  • EUR 376.80
  • EUR 944.40
  • EUR 493.20
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx131778
  • EUR 393.60
  • EUR 1011.60
  • EUR 526.80
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx131779
  • EUR 393.60
  • EUR 1011.60
  • EUR 526.80
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx131780
  • EUR 393.60
  • EUR 1011.60
  • EUR 526.80
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx129539
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

4-APA855Mu01
  • EUR 952.20
  • EUR 378.00
  • EUR 3240.77
  • EUR 1160.26
  • EUR 2200.51
  • EUR 712.80
  • EUR 7921.92
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

4-APA855Mu61
  • EUR 952.20
  • EUR 378.00
  • EUR 3240.77
  • EUR 1160.26
  • EUR 2200.51
  • EUR 712.80
  • EUR 7921.92
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

4-APA855Ra61
  • EUR 980.16
  • EUR 386.40
  • EUR 3345.60
  • EUR 1195.20
  • EUR 2270.40
  • EUR 732.00
  • EUR 8184.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells

Eukaryotic Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

4-EPA855Mu61
  • EUR 926.40
  • EUR 372.00
  • EUR 3144.00
  • EUR 1128.00
  • EUR 2136.00
  • EUR 696.00
  • EUR 7680.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand expressed in: 293F cell

Recombinant Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

4-RPA855Hu01
  • EUR 980.16
  • EUR 386.40
  • EUR 3345.60
  • EUR 1195.20
  • EUR 2270.40
  • EUR 732.00
  • EUR 8184.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Receptor Activator Of Nuclear Factor Kappa B Ligand expressed in: E.coli

Recombinant Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

4-RPA855Mu01
  • EUR 582.34
  • EUR 279.60
  • EUR 1853.76
  • EUR 697.92
  • EUR 1275.84
  • EUR 465.60
  • EUR 4454.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand expressed in: E.coli

Recombinant Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

4-RPA855Ra01
  • EUR 550.08
  • EUR 271.20
  • EUR 1732.80
  • EUR 657.60
  • EUR 1195.20
  • EUR 444.00
  • EUR 4152.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Receptor Activator Of Nuclear Factor Kappa B Ligand expressed in: E.coli

Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx178216
  • EUR 1362.00
  • EUR 661.20
  • 1 mg
  • 200 ug

Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx178217
  • EUR 1412.40
  • EUR 693.60
  • 1 mg
  • 200 ug

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx270109
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx270204
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx270211
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx270212
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (FITC)

20-abx270415
  • EUR 678.00
  • EUR 794.40
  • EUR 376.80
  • EUR 1228.80
  • EUR 493.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (FITC)

20-abx270525
  • EUR 678.00
  • EUR 794.40
  • EUR 376.80
  • EUR 1228.80
  • EUR 493.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (APC)

20-abx270647
  • EUR 910.80
  • EUR 1078.80
  • EUR 460.80
  • EUR 1746.00
  • EUR 644.40
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (APC)

20-abx270757
  • EUR 910.80
  • EUR 1078.80
  • EUR 460.80
  • EUR 1746.00
  • EUR 644.40
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (PE)

20-abx270879
  • EUR 794.40
  • EUR 927.60
  • EUR 427.20
  • EUR 1479.60
  • EUR 560.40
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (PE)

20-abx270989
  • EUR 794.40
  • EUR 927.60
  • EUR 427.20
  • EUR 1479.60
  • EUR 560.40
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Antibody

20-abx174341
  • EUR 944.40
  • EUR 493.20
  • 1 mg
  • 200 ug

Hamster receptor activator of nuclear factor kappa B ligand ELIS

ELA-E0855Ha 96 Tests
EUR 1113.6

Rabbit receptor activator of nuclear factor kappa B ligand ELISA

ELA-E0855Rb 96 Tests
EUR 1113.6

Mouse receptor activator of nuclear factor kappa B ELISA Kit

ELA-E2057m 96 Tests
EUR 1038

Rat Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Protein

20-abx168481
  • EUR 777.60
  • EUR 326.40
  • EUR 2331.60
  • EUR 910.80
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Protein

20-abx167262
  • EUR 811.20
  • EUR 343.20
  • EUR 2498.40
  • EUR 961.20
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Protein

20-abx068827
  • EUR 1345.20
  • EUR 493.20
  • EUR 4468.80
  • EUR 1629.60
  • EUR 910.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (Biotin)

20-abx274452
  • EUR 427.20
  • EUR 243.60
  • EUR 1095.60
  • EUR 560.40
  • EUR 360.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (Biotin)

20-abx274550
  • EUR 410.40
  • EUR 243.60
  • EUR 1028.40
  • EUR 526.80
  • EUR 343.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Chicken Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Protein

20-abx654908
  • EUR 777.60
  • EUR 326.40
  • EUR 2397.60
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) Protein (Active)

20-abx655815
  • EUR 1279.20
  • EUR 477.60
  • EUR 4236.00
  • EUR 1545.60
  • EUR 878.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Protein

20-abx651561
  • EUR 1262.40
  • EUR 460.80
  • EUR 4202.40
  • EUR 1528.80
  • EUR 861.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Receptor Activator of Nuclear Factor Kappa B (RANk) CLIA Kit

abx196215-96tests 96 tests
EUR 990

Human Receptor Activator of Nuclear Factor Kappa B (RANκ) CLIA Kit

abx196216-96tests 96 tests
EUR 990

Mouse Receptor Activator of Nuclear Factor Kappa B (RANκ) CLIA Kit

abx196217-96tests 96 tests
EUR 990

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (FITC)

20-abx270407
  • EUR 627.60
  • EUR 727.20
  • EUR 360.00
  • EUR 1128.00
  • EUR 460.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (FITC)

20-abx270502
  • EUR 627.60
  • EUR 727.20
  • EUR 360.00
  • EUR 1128.00
  • EUR 460.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (FITC)

20-abx270509
  • EUR 627.60
  • EUR 727.20
  • EUR 360.00
  • EUR 1128.00
  • EUR 460.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (FITC)

20-abx270510
  • EUR 627.60
  • EUR 727.20
  • EUR 360.00
  • EUR 1128.00
  • EUR 460.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (APC)

20-abx270639
  • EUR 844.80
  • EUR 994.80
  • EUR 444.00
  • EUR 1596.00
  • EUR 594.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (APC)

20-abx270734
  • EUR 844.80
  • EUR 994.80
  • EUR 444.00
  • EUR 1596.00
  • EUR 594.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (APC)

20-abx270741
  • EUR 844.80
  • EUR 994.80
  • EUR 444.00
  • EUR 1596.00
  • EUR 594.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (APC)

20-abx270742
  • EUR 844.80
  • EUR 994.80
  • EUR 444.00
  • EUR 1596.00
  • EUR 594.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (PE)

20-abx270871
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (PE)

20-abx270966
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (PE)

20-abx270973
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (PE)

20-abx270974
  • EUR 727.20
  • EUR 861.60
  • EUR 393.60
  • EUR 1362.00
  • EUR 526.80
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody Pair

20-abx370222
  • EUR 1914.00
  • EUR 1228.80
  • 10 × 96 tests
  • 5 × 96 tests

Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody Pair

20-abx370472
  • EUR 2047.20
  • EUR 1312.80
  • 10 × 96 tests
  • 5 × 96 tests

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) CLIA Kit

20-abx493431
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) CLIA Kit

20-abx493432
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

DLR-RANk-Hu-48T 48T
EUR 620.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

DLR-RANk-Hu-96T 96T
EUR 807.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

DLR-RANk-Ra-48T 48T
EUR 658.8
Description: A sandwich quantitative ELISA assay kit for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

DLR-RANk-Ra-96T 96T
EUR 861.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse RANκ(Receptor Activator of Nuclear Factor Kappa B) ELISA Kit

EM0163 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 37.5pg/ml

Receptor Activator Of Nuclear Factor Kappa B (RANk) Monoclonal Antibody (Human)

4-MAC057Hu22
  • EUR 306.00
  • EUR 3170.40
  • EUR 786.00
  • EUR 386.40
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Receptor Activator Of Nuclear Factor Kappa B (RANk)

Rat receptor activator of nuclear factor kappa B(RANK)ELISA Kit

GA-E0296RT-48T 48T
EUR 380.4

Rat receptor activator of nuclear factor kappa B(RANK)ELISA Kit

GA-E0296RT-96T 96T
EUR 595.2

Receptor Activator Of Nuclear Factor Kappa B (RANk) Polyclonal Antibody (Mouse)

4-PAC057Mu01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Receptor Activator Of Nuclear Factor Kappa B (RANk)

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

RD-RANk-Hu-48Tests 48 Tests
EUR 625.2

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

RD-RANk-Hu-96Tests 96 Tests
EUR 867.6

Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

RD-RANk-Ra-48Tests 48 Tests
EUR 668.4

Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

RD-RANk-Ra-96Tests 96 Tests
EUR 930

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

RDR-RANk-Hu-48Tests 48 Tests
EUR 652.8

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

RDR-RANk-Hu-96Tests 96 Tests
EUR 907.2

Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

RDR-RANk-Ra-48Tests 48 Tests
EUR 699.6

Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

RDR-RANk-Ra-96Tests 96 Tests
EUR 973.2

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

SEC057Hu-10x96wellstestplate 10x96-wells test plate
EUR 5677.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids.

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

SEC057Hu-1x48wellstestplate 1x48-wells test plate
EUR 572.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids.

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

SEC057Hu-1x96wellstestplate 1x96-wells test plate
EUR 766.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids.

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

SEC057Hu-5x96wellstestplate 5x96-wells test plate
EUR 3090.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids.

Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

4-SEC057Hu
  • EUR 5738.40
  • EUR 3031.20
  • EUR 768.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

SEC057Ra-10x96wellstestplate 10x96-wells test plate
EUR 6149.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids.

Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

SEC057Ra-1x48wellstestplate 1x48-wells test plate
EUR 611.57
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids.

Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

SEC057Ra-1x96wellstestplate 1x96-wells test plate
EUR 822.24
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids.

Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

SEC057Ra-5x96wellstestplate 5x96-wells test plate
EUR 3340.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids.

Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit

4-SEC057Ra
  • EUR 6210.00
  • EUR 3280.80
  • EUR 823.20
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Human Receptor Activator Of Nuclear Factor Kappa B(RANk)ELISA Kit

QY-E03143 96T
EUR 433.2

Rat receptor activator of nuclear factor kappa B(RANK)ELISA Kit

QY-E11356 96T
EUR 433.2

Mouse receptor activator of nuclear factor kappa B(RANK)ELISA Kit

QY-E21307 96T
EUR 433.2

Rat Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Protein (Active)

20-abx655816
  • EUR 1345.20
  • EUR 493.20
  • EUR 4468.80
  • EUR 1629.60
  • EUR 910.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) CLIA Kit

abx196331-96tests 96 tests
EUR 990

Human Receptor Activator of Nuclear Factor Kappa B Ligand (RANκL) CLIA Kit

abx196332-96tests 96 tests
EUR 990

Mouse Receptor Activator of Nuclear Factor Kappa B Ligand (RANκL) CLIA Kit

abx196333-96tests 96 tests
EUR 990

Dog Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) ELISA Kit

20-abx585251
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Dog Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) CLIA Kit

20-abx496633
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) CLIA Kit

20-abx492142
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human receptor activator of nuclear factor kappa B ligand,RANKL ELISA Kit

201-12-0621 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Hamster receptor activator of nuclear factor kappa B ligand,RANKL ELISA Kit

CN-00084O1 96T
EUR 590.4

Hamster receptor activator of nuclear factor kappa B ligand,RANKL ELISA Kit

CN-00084O2 48T
EUR 409.2

Rabbit receptor activator of nuclear factor kappa B ligand, RANKL ELISA Kit

CSB-E11253Rb-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rabbit receptor activator of nuclear factor kappa B ligand, RANKL in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rabbit receptor activator of nuclear factor kappa B ligand, RANKL ELISA Kit

1-CSB-E11253Rb
  • EUR 1160.40
  • EUR 7110.00
  • EUR 3760.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rabbit receptor activator of nuclear factor kappa B ligand, RANKL in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse receptor activator of nuclear factor kappa B ligand,RANKL ELISA Kit

CN-02787M1 96T
EUR 565.2

Mouse receptor activator of nuclear factor kappa B ligand,RANKL ELISA Kit

CN-02787M2 48T
EUR 386.4

Human receptor activator of nuclear factor kappa B ligand,RANKL ELISA Kit

CN-04668H1 96T
EUR 573.6

Human receptor activator of nuclear factor kappa B ligand,RANKL ELISA Kit

CN-04668H2 48T
EUR 394.8

Rat receptor activator of nuclear factor kappa B ligand,RANKL ELISA Kit

CN-01911R1 96T
EUR 586.8

Rat receptor activator of nuclear factor kappa B ligand,RANKL ELISA Kit

CN-01911R2 48T
EUR 405.6

Human Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) ELISA Kit

DLR-RANkL-Hu-48T 48T
EUR 574.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) ELISA Kit

DLR-RANkL-Hu-96T 96T
EUR 745.2
Description: A sandwich quantitative ELISA assay kit for detection of Human Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) ELISA Kit

DLR-RANkL-Mu-48T 48T
EUR 586.8
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids.

Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) ELISA Kit

DLR-RANkL-Mu-96T 96T
EUR 762
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids.

Rat Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) ELISA Kit

DLR-RANkL-Ra-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rat Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) ELISA Kit

DLR-RANkL-Ra-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Rat Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

CLIA kit for Human RAN? (Receptor Activator of Nuclear Factor Kappa B)

E-CL-H1405 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human RAN? (Receptor Activator of Nuclear Factor Kappa B) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Mouse RAN? (Receptor Activator of Nuclear Factor Kappa B)

E-CL-M0402 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Mouse RAN? (Receptor Activator of Nuclear Factor Kappa B) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Rat RAN? (Receptor Activator of Nuclear Factor Kappa B)

E-CL-R0110 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Rat RAN? (Receptor Activator of Nuclear Factor Kappa B) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human RANk (Receptor Activator Of Nuclear Factor Kappa B)

ELK2934 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Receptor Activator Of Nuclear Factor Kappa B from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Rat RANk (Receptor Activator Of Nuclear Factor Kappa B)

ELK5786 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Receptor Activator Of Nuclear Factor Kappa B from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Monoclonal Antibody (Human)

4-MAA855Hu21
  • EUR 289.20
  • EUR 2900.40
  • EUR 724.80
  • EUR 361.20
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Monoclonal Antibody (Rat)

4-MAA855Ra26
  • EUR 301.20
  • EUR 3106.80
  • EUR 771.60
  • EUR 380.40
  • EUR 259.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Rat Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Polyclonal Antibody (Mouse)

4-PAA855Mu01
  • EUR 283.20
  • EUR 2805.60
  • EUR 703.20
  • EUR 352.80
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Polyclonal Antibody (Rat)

4-PAA855Ra01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)
Taken collectively, our outcomes introduced that NS2A and NS4A critically antagonize MDA5/RIG-I-mediated NF-κB manufacturing and people proteins could appear to be managed in numerous mechanisms. This research might assist perceive the mechanisms how ZIKV controls innate immune responses and could also be supplied for improvement of ZIKV-specific medicines.