Autoreactive B cells mediate autoimmune pathology, however precisely how stays unknown. A trademark of rheumatoid arthritis (RA), a standard autoimmune illness, is the presence of disease-specific anticitrullinated protein antibodies (ACPAs). Right here, we confirmed that ACPA-positive B cells in sufferers with RA strongly expressed T cell-stimulating ligands, produced considerable proinflammatory cytokines, and have been proliferative whereas escaping inhibitory alerts.
This activated state was discovered at totally different levels in numerous levels of illness: highest in sufferers with recent-onset RA, reasonable in sufferers with established RA, and much much less pronounced in ACPA-positive people “in danger” for growing illness. The activated autoreactive B cell response persevered in sufferers who achieved medical remission with standard remedy. ACPA-positive B cells in blood and synovial fluid secreted elevated quantities of the chemoattractant interleukin-8, which attracted neutrophils, probably the most considerable immune cell in arthritic joints.
Tetanus toxoid-specific B cells from the identical sufferers exhibited properties of reminiscence B cells with out the activation and proliferation phenotype, however these cells transiently acquired an analogous proliferative phenotype upon booster vaccination. Collectively, these knowledge indicated that steady antigenic triggering of autoreactive B cells happens in human autoimmune illness and assist the rising idea of immunological exercise that persists beneath remedy even in medical remission, which can revise our present idea of remedy targets for future therapeutic interventions. As well as, our knowledge pointed to a pathogenic position of ACPA-positive B cells within the inflammatory illness course of underlying RA and favor approaches that intention at their antigen-specific inactivation or depletion.
Destiny Mapping Quantifies the Dynamics of B Cell Growth and Activation all through Life
Follicular mature (FM) and germinal middle (GC) B cells underpin humoral immunity, however the dynamics of their era and upkeep should not clearly outlined. Right here, we exploited a fate-mapping system in mice that tracks B cells as they grow to be peripheral subsets, along with a cell division destiny reporter mouse and mathematical fashions. We discover that FM cells are kinetically homogeneous, recirculate freely, are regularly replenished from transitional populations, and self-renew not often.
In distinction, GC B cell lineages persist for weeks with fast turnover and site-specific dynamics. These within the spleen derive from transitional cells and are kinetically homogeneous, whereas these in lymph nodes derive from FM B cells and comprise each transient and protracted clones. These variations probably derive from the character of antigen publicity on the totally different websites. Our integrative method additionally reveals how the host setting drives cell-extrinsic, age-related adjustments in B cell homeostasis. Lack of practical β-cell mass is a trademark of Kind 1 and Kind 2 Diabetes.
Macrophages play an integral position within the upkeep or destruction of pancreatic β-cells. The impact of the macrophage β-cell interplay depends on the activation state of the macrophage. Macrophages will be activated throughout a spectrum, from pro-inflammatory to anti-inflammatory and tissue transforming. The components secreted by these differentially activated macrophages and their impact on β-cells outline the impact on practical β-cell mass. On this evaluate, the spectrum of macrophage activation is mentioned, as are the optimistic and destructive results on β-cell survival, enlargement, and performance in addition to the outlined components launched from macrophages that impinge on practical β-cell mass.
Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis
Zika Virus NS2A and NS4A Downregulate the Promoter Exercise of Nuclear Issue Kappa-Gentle-Chain-Enhancer of Activated B Cells
Since ZIKV was first detected at Uganda in 1947 and, critical outbreaks have globally occurred within the Yap Island, the French Polynesia and Brazil. Despite the fact that the variety of an infection and unfold of ZIKV have sharply rise, the pathogenesis or replication mechanisms ZIKV haven’t been effectively studied. Zika virus (ZIKV) is just lately highlighted Flavivirus, a mosquito born rising virus inflicting microcephaly and the Guillain-Barre syndrome in fetuses and adults, respectively. ZIKV polyprotein consists of three structural proteins named C, prM and E and 7 nonstructural proteins named NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5 in 11-kb single-stranded optimistic sense RNA genome.
The operate of particular person ZIKV genes on the host innate immune responses have been barely studied. On this research, we investigated the modulations of the NF-κB promoter exercise associated by the MDA5/RIG-I signaling pathway. Within the outcomes, two nonstructural proteins, NS2A and NS4A, dramatically suppressed the NF-κB promoter exercise by inhibiting signaling components on MDA5/RIG-I signaling pathway associated to activation of NF-κB. Curiously, NS2A suppressed all parts of MDA5/RIG-I signaling pathway, however NS4A inhibited most signaling molecules, besides IKKε and IRF3-5D. As well as, each NS2A and NS4A down-regulated MDA5 associated NF-κB promoter exercise in dose-dependent method.
 Antibody) Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
|
20-abx270117 |
Abbexa |
-
EUR 594.00
-
EUR 693.60
-
EUR 343.20
-
EUR 1062.00
-
EUR 444.00
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
|
20-abx270227 |
Abbexa |
-
EUR 594.00
-
EUR 693.60
-
EUR 343.20
-
EUR 1062.00
-
EUR 444.00
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
|
20-abx104350 |
Abbexa |
-
EUR 526.80
-
EUR 159.60
-
EUR 1479.60
-
EUR 710.40
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Antibody) Receptor Activator Of Nuclear Factor Kappa B (RANk) Antibody |
|
20-abx174339 |
Abbexa |
-
EUR 410.40
-
EUR 1028.40
-
EUR 526.80
-
EUR 184.80
-
EUR 309.60
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Receptor Activator Of Nuclear Factor Kappa B (RANk) Antibody |
|
20-abx174340 |
Abbexa |
|
|
|
|
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
|
20-abx128602 |
Abbexa |
-
EUR 510.00
-
EUR 159.60
-
EUR 1446.00
-
EUR 693.60
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
|
20-abx131781 |
Abbexa |
-
EUR 410.40
-
EUR 1028.40
-
EUR 526.80
-
EUR 184.80
-
EUR 309.60
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody |
|
20-abx130205 |
Abbexa |
-
EUR 543.60
-
EUR 159.60
-
EUR 1562.40
-
EUR 744.00
-
EUR 410.40
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Antibody (PE)) Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (PE) |
|
20-abx270879 |
Abbexa |
-
EUR 794.40
-
EUR 927.60
-
EUR 427.20
-
EUR 1479.60
-
EUR 560.40
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (PE) |
|
20-abx270989 |
Abbexa |
-
EUR 794.40
-
EUR 927.60
-
EUR 427.20
-
EUR 1479.60
-
EUR 560.40
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
 Antibody (APC)) Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (APC) |
|
20-abx270647 |
Abbexa |
-
EUR 910.80
-
EUR 1078.80
-
EUR 460.80
-
EUR 1746.00
-
EUR 644.40
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (APC) |
|
20-abx270757 |
Abbexa |
-
EUR 910.80
-
EUR 1078.80
-
EUR 460.80
-
EUR 1746.00
-
EUR 644.40
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
) Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
|
4-RPC057Hu01 |
Cloud-Clone |
-
EUR 571.58
-
EUR 276.00
-
EUR 1813.44
-
EUR 684.48
-
EUR 1248.96
-
EUR 458.40
-
EUR 4353.60
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human Receptor Activator Of Nuclear Factor Kappa B expressed in: E.coli |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
|
4-RPC057Mu01 |
Cloud-Clone |
-
EUR 593.09
-
EUR 282.00
-
EUR 1894.08
-
EUR 711.36
-
EUR 1302.72
-
EUR 472.80
-
EUR 4555.20
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse Receptor Activator Of Nuclear Factor Kappa B expressed in: E.coli |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
|
4-RPC057Ra01 |
Cloud-Clone |
-
EUR 614.59
-
EUR 288.00
-
EUR 1974.72
-
EUR 738.24
-
EUR 1356.48
-
EUR 487.20
-
EUR 4756.80
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Rat Receptor Activator Of Nuclear Factor Kappa B expressed in: E.coli |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
|
RPU52109-100ug |
Biomatik Corporation |
100ug |
EUR 517 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
|
RPU52109-1mg |
Biomatik Corporation |
1mg |
EUR 2293.2 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
|
RPU52109-50ug |
Biomatik Corporation |
50ug |
EUR 415.8 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
|
RPU53947-100ug |
Biomatik Corporation |
100ug |
EUR 566.5 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
|
RPU53947-1mg |
Biomatik Corporation |
1mg |
EUR 2511.6 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
|
RPU53947-50ug |
Biomatik Corporation |
50ug |
EUR 455.4 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
|
RPU43561-100ug |
Biomatik Corporation |
100ug |
EUR 542.3 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
|
RPU43561-1mg |
Biomatik Corporation |
1mg |
EUR 2402.4 |
Recombinant Receptor Activator Of Nuclear Factor Kappa B (RANk) |
|
RPU43561-50ug |
Biomatik Corporation |
50ug |
EUR 435.6 |
 Rat Receptor Activator Of Nuclear Factor Kappa B ELISA Kit |
|
IRTRANKKT |
Innovative research |
each |
EUR 790 |
|
|
|
Description: Rat Receptor Activator Of Nuclear Factor Kappa B ELISA Kit |
 Antibody (FITC)) Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (FITC) |
|
20-abx270415 |
Abbexa |
-
EUR 678.00
-
EUR 794.40
-
EUR 376.80
-
EUR 1228.80
-
EUR 493.20
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
Receptor Activator of Nuclear Factor Kappa B (RANk) Antibody (FITC) |
|
20-abx270525 |
Abbexa |
-
EUR 678.00
-
EUR 794.40
-
EUR 376.80
-
EUR 1228.80
-
EUR 493.20
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
 Mouse receptor activator of nuclear factor kappa B ELISA Kit |
|
ELA-E2057m |
Lifescience Market |
96 Tests |
EUR 1038 |
 Human Receptor Activator Of Nuclear Factor Kappa B ELISA Kit |
|
IHURANKKT |
Innovative research |
each |
EUR 733 |
|
|
|
Description: Human Receptor Activator Of Nuclear Factor Kappa B ELISA Kit |
 Protein) Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) Protein |
|
20-abx168512 |
Abbexa |
-
EUR 861.60
-
EUR 343.20
-
EUR 2665.20
-
EUR 1028.40
-
EUR 610.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
) Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
|
4-APA855Mu01 |
Cloud-Clone |
-
EUR 952.20
-
EUR 378.00
-
EUR 3240.77
-
EUR 1160.26
-
EUR 2200.51
-
EUR 712.80
-
EUR 7921.92
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells |
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
|
4-APA855Mu61 |
Cloud-Clone |
-
EUR 952.20
-
EUR 378.00
-
EUR 3240.77
-
EUR 1160.26
-
EUR 2200.51
-
EUR 712.80
-
EUR 7921.92
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse Receptor Activator Of Nuclear Factor Kappa B Ligand expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells |
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
|
4-APA855Ra61 |
Cloud-Clone |
-
EUR 980.16
-
EUR 386.40
-
EUR 3345.60
-
EUR 1195.20
-
EUR 2270.40
-
EUR 732.00
-
EUR 8184.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Rat Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) expressed in: Available from E.coli, Yeast, Baculovirus and Mammalian cells |
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
|
RPU55615-100ug |
Biomatik Corporation |
100ug |
EUR 953.7 |
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
|
RPU55615-1mg |
Biomatik Corporation |
1mg |
EUR 4829.5 |
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
|
RPU55615-50ug |
Biomatik Corporation |
50ug |
EUR 743.1 |
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
|
RPU55616-100ug |
Biomatik Corporation |
100ug |
EUR 1267.2 |
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
|
RPU55616-1mg |
Biomatik Corporation |
1mg |
EUR 4992 |
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
|
RPU55616-50ug |
Biomatik Corporation |
50ug |
EUR 768 |
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
|
RPU55617-100ug |
Biomatik Corporation |
100ug |
EUR 651.2 |
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
|
RPU55617-1mg |
Biomatik Corporation |
1mg |
EUR 3294.2 |
Active Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) |
|
RPU55617-50ug |
Biomatik Corporation |
50ug |
EUR 506.9 |
 Antibody) Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx270109 |
Abbexa |
-
EUR 560.40
-
EUR 644.40
-
EUR 326.40
-
EUR 978.00
-
EUR 427.20
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx270204 |
Abbexa |
-
EUR 560.40
-
EUR 644.40
-
EUR 326.40
-
EUR 978.00
-
EUR 427.20
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx270211 |
Abbexa |
-
EUR 560.40
-
EUR 644.40
-
EUR 326.40
-
EUR 978.00
-
EUR 427.20
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx270212 |
Abbexa |
-
EUR 560.40
-
EUR 644.40
-
EUR 326.40
-
EUR 978.00
-
EUR 427.20
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
 Antibody) Receptor Activator of Nuclear Factor Kappa B Ligand (RANKL) Antibody |
|
abx237108-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
|
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx104600 |
Abbexa |
-
EUR 477.60
-
EUR 159.60
-
EUR 1328.40
-
EUR 644.40
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Antibody) Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx174341 |
Abbexa |
|
|
|
|
Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx178216 |
Abbexa |
|
|
|
|
Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx178217 |
Abbexa |
|
|
|
|
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx129539 |
Abbexa |
-
EUR 493.20
-
EUR 159.60
-
EUR 1362.00
-
EUR 661.20
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx131777 |
Abbexa |
-
EUR 376.80
-
EUR 944.40
-
EUR 493.20
-
EUR 184.80
-
EUR 309.60
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx131778 |
Abbexa |
-
EUR 393.60
-
EUR 1011.60
-
EUR 526.80
-
EUR 184.80
-
EUR 309.60
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx131779 |
Abbexa |
-
EUR 393.60
-
EUR 1011.60
-
EUR 526.80
-
EUR 184.80
-
EUR 309.60
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx131780 |
Abbexa |
-
EUR 393.60
-
EUR 1011.60
-
EUR 526.80
-
EUR 184.80
-
EUR 309.60
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody |
|
20-abx130179 |
Abbexa |
-
EUR 510.00
-
EUR 159.60
-
EUR 1412.40
-
EUR 693.60
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Protein) Mouse Receptor Activator Of Nuclear Factor Kappa B (RANk) Protein |
|
20-abx068826 |
Abbexa |
-
EUR 828.00
-
EUR 343.20
-
EUR 2548.80
-
EUR 978.00
-
EUR 594.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Protein) Human Receptor Activator Of Nuclear Factor Kappa B (RANk) Protein |
|
20-abx166643 |
Abbexa |
-
EUR 794.40
-
EUR 326.40
-
EUR 2448.00
-
EUR 944.40
-
EUR 577.20
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Monoclonal Antibody) Receptor Activator Of Nuclear Factor Kappa B (RANk) Monoclonal Antibody |
|
CAU30364-100ul |
Biomatik Corporation |
100ul |
EUR 248.6 |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Monoclonal Antibody |
|
CAU30364-200ul |
Biomatik Corporation |
200ul |
EUR 310.8 |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Monoclonal Antibody |
|
CAU29557-100ul |
Biomatik Corporation |
100ul |
EUR 248.6 |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Monoclonal Antibody |
|
CAU29557-200ul |
Biomatik Corporation |
200ul |
EUR 310.8 |
 Polyclonal Antibody) Receptor Activator Of Nuclear Factor Kappa B (RANk) Polyclonal Antibody |
|
CAU24765-100ul |
Biomatik Corporation |
100ul |
EUR 255.4 |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Polyclonal Antibody |
|
CAU24765-200ul |
Biomatik Corporation |
200ul |
EUR 319.2 |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Polyclonal Antibody |
|
CAU24766-100ul |
Biomatik Corporation |
100ul |
EUR 241.9 |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Polyclonal Antibody |
|
CAU24766-200ul |
Biomatik Corporation |
200ul |
EUR 302.4 |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Polyclonal Antibody |
|
CAU24767-100ul |
Biomatik Corporation |
100ul |
EUR 235.2 |
Receptor Activator Of Nuclear Factor Kappa B (RANk) Polyclonal Antibody |
|
CAU24767-200ul |
Biomatik Corporation |
200ul |
EUR 294 |
 Hamster receptor activator of nuclear factor kappa B ligand ELIS |
|
ELA-E0855Ha |
Lifescience Market |
96 Tests |
EUR 1113.6 |
 Rabbit receptor activator of nuclear factor kappa B ligand ELISA |
|
ELA-E0855Rb |
Lifescience Market |
96 Tests |
EUR 1113.6 |
 CLIA Kit) Rat Receptor Activator of Nuclear Factor Kappa B (RANk) CLIA Kit |
|
abx196215-96tests |
Abbexa |
96 tests |
EUR 990 |
|
|
 CLIA Kit) Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) CLIA Kit |
|
20-abx493432 |
Abbexa |
-
EUR 10282.80
-
EUR 5472.00
-
EUR 1262.40
|
- 10 × 96 tests
- 5 × 96 tests
- 96 tests
|
|
|
 ELISA Kit) Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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DLR-RANk-Ra-48T |
DL Develop |
48T |
EUR 658.8 |
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Description: A sandwich quantitative ELISA assay kit for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in samples from tissue homogenates, cell lysates or other biological fluids. |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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DLR-RANk-Ra-96T |
DL Develop |
96T |
EUR 861.6 |
|
|
|
Description: A sandwich quantitative ELISA assay kit for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in samples from tissue homogenates, cell lysates or other biological fluids. |
ELISA Kit) Rat receptor activator of nuclear factor kappa B(RANK)ELISA Kit |
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GA-E0296RT-48T |
GenAsia Biotech |
48T |
EUR 380.4 |
Rat receptor activator of nuclear factor kappa B(RANK)ELISA Kit |
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GA-E0296RT-96T |
GenAsia Biotech |
96T |
EUR 595.2 |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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SEC057Ra-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 6149.04 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids. |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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SEC057Ra-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 611.57 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids. |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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SEC057Ra-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 822.24 |
|
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids. |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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SEC057Ra-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 3340.08 |
|
|
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids. |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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4-SEC057Ra |
Cloud-Clone |
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EUR 6210.00
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EUR 3280.80
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EUR 823.20
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- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species. |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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RD-RANk-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 668.4 |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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RD-RANk-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 930 |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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RDR-RANk-Ra-48Tests |
Reddot Biotech |
48 Tests |
EUR 699.6 |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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RDR-RANk-Ra-96Tests |
Reddot Biotech |
96 Tests |
EUR 973.2 |
Rat receptor activator of nuclear factor kappa B(RANK)ELISA Kit |
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QY-E11356 |
Qayee Biotechnology |
96T |
EUR 433.2 |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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RDR-RANk-Ra-48T |
Reddot Biotech |
48T |
EUR 512.09 |
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Description: tissue homogenates, cell lysates and other biological fluids. |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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RDR-RANk-Ra-96T |
Reddot Biotech |
96T |
EUR 731.54 |
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Description: tissue homogenates, cell lysates and other biological fluids. |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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RD-RANk-Ra-48T |
Reddot Biotech |
48T |
EUR 487.7 |
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|
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Description: tissue homogenates, cell lysates and other biological fluids. |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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RD-RANk-Ra-96T |
Reddot Biotech |
96T |
EUR 696.7 |
|
|
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Description: tissue homogenates, cell lysates and other biological fluids. |
 ELISA Kit) Rat RANκ (Receptor Activator of Nuclear Factor Kappa B) ELISA Kit |
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EKE62038-5x96T |
Biomatik Corporation |
5x96T |
EUR 3124.08 |
Rat RANκ (Receptor Activator of Nuclear Factor Kappa B) ELISA Kit |
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EKE62038-96T |
Biomatik Corporation |
96T |
EUR 657.7 |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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DL-RANk-Ra |
DL Develop |
96T |
EUR 475 |
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|
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Description: tissue homogenates, cell lysates or other biological fluids. |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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DLR-RANk-Ra |
DL Develop |
96T |
EUR 499 |
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|
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Description: tissue homogenates, cell lysates or other biological fluids. |
 Rat receptor activator of nuclear factor kappa B,RANK ELISA Kit |
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YLA0645RA-48T |
Shanghai YL Biotech |
48T |
EUR 465 |
Rat receptor activator of nuclear factor kappa B,RANK ELISA Kit |
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YLA0645RA-96T |
Shanghai YL Biotech |
96T |
EUR 600 |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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EKN48129-48T |
Biomatik Corporation |
48T |
EUR 410.83 |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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EKN48129-5x96T |
Biomatik Corporation |
5x96T |
EUR 2787.78 |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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EKN48129-96T |
Biomatik Corporation |
96T |
EUR 586.9 |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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EKU07018-48T |
Biomatik Corporation |
48T |
EUR 603.26 |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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EKU07018-5x96T |
Biomatik Corporation |
5x96T |
EUR 4093.55 |
Rat Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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EKU07018-96T |
Biomatik Corporation |
96T |
EUR 861.8 |
ELISA Kit) Rat Receptor activator of nuclear factor kappa B(RANK)ELISA Kit |
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SL1116Ra |
Sunlong |
- |
EUR 498 |
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 ELISA Kit) Rat RANk(Receptor Activator Of Nuclear Factor Kappa B) ELISA Kit |
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ELK5786-48T |
ELK Biotech |
48T |
Ask for price |
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Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat RANk. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat RANk. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat RANk, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat RANk in the samples is then determined by comparing the OD of the samples to the standard curve. |
Rat RANk(Receptor Activator Of Nuclear Factor Kappa B) ELISA Kit |
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ELK5786-96T |
ELK Biotech |
96T |
Ask for price |
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Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat RANk. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat RANk. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat RANk, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat RANk in the samples is then determined by comparing the OD of the samples to the standard curve. |
 CLIA Kit) Human Receptor Activator of Nuclear Factor Kappa B (RANκ) CLIA Kit |
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abx196216-96tests |
Abbexa |
96 tests |
EUR 990 |
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 CLIA Kit) Mouse Receptor Activator of Nuclear Factor Kappa B (RANκ) CLIA Kit |
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abx196217-96tests |
Abbexa |
96 tests |
EUR 990 |
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 CLIA Kit) Human Receptor Activator Of Nuclear Factor Kappa B (RANk) CLIA Kit |
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20-abx493431 |
Abbexa |
-
EUR 9567.60
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EUR 5095.20
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EUR 1177.20
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- 10 × 96 tests
- 5 × 96 tests
- 96 tests
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 Antibody (PE)) Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (PE) |
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20-abx270871 |
Abbexa |
-
EUR 727.20
-
EUR 861.60
-
EUR 393.60
-
EUR 1362.00
-
EUR 526.80
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
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Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (PE) |
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20-abx270966 |
Abbexa |
-
EUR 727.20
-
EUR 861.60
-
EUR 393.60
-
EUR 1362.00
-
EUR 526.80
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (PE) |
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20-abx270973 |
Abbexa |
-
EUR 727.20
-
EUR 861.60
-
EUR 393.60
-
EUR 1362.00
-
EUR 526.80
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
|
|
Receptor Activator of Nuclear Factor Kappa B Ligand (RANkL) Antibody (PE) |
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20-abx270974 |
Abbexa |
-
EUR 727.20
-
EUR 861.60
-
EUR 393.60
-
EUR 1362.00
-
EUR 526.80
|
- 100 tests
- 200 tests
- 25 tests
- 500 tests
- 50 tests
|
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 ELISA Kit) Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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DLR-RANk-Hu-48T |
DL Develop |
48T |
EUR 620.4 |
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Description: A sandwich quantitative ELISA assay kit for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in samples from tissue homogenates, cell lysates or other biological fluids. |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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DLR-RANk-Hu-96T |
DL Develop |
96T |
EUR 807.6 |
|
|
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Description: A sandwich quantitative ELISA assay kit for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in samples from tissue homogenates, cell lysates or other biological fluids. |
 ELISA Kit) Mouse RANκ(Receptor Activator of Nuclear Factor Kappa B) ELISA Kit |
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EM0163 |
FN Test |
96T |
EUR 628.92 |
|
|
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 37.5pg/ml |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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SEC057Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5677.8 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids. |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
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SEC057Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 572.76 |
|
|
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids. |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
|
SEC057Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 766.8 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids. |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
|
SEC057Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 3090.6 |
|
|
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in Tissue homogenates, cell lysates and other biological fluids. |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
|
4-SEC057Hu |
Cloud-Clone |
-
EUR 5738.40
-
EUR 3031.20
-
EUR 768.00
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Receptor Activator Of Nuclear Factor Kappa B (RANk) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
|
RD-RANk-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 625.2 |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
|
RD-RANk-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 867.6 |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
|
RDR-RANk-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 652.8 |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
|
RDR-RANk-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 907.2 |
ELISA Kit) Mouse receptor activator of nuclear factor kappa B(RANK)ELISA Kit |
|
QY-E21307 |
Qayee Biotechnology |
96T |
EUR 433.2 |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
|
RDR-RANk-Hu-48T |
Reddot Biotech |
48T |
EUR 475.34 |
|
|
|
Description: tissue homogenates, cell lysates and other biological fluids. |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
|
RDR-RANk-Hu-96T |
Reddot Biotech |
96T |
EUR 679.04 |
|
|
|
Description: tissue homogenates, cell lysates and other biological fluids. |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
|
RD-RANk-Hu-48T |
Reddot Biotech |
48T |
EUR 452.7 |
|
|
|
Description: tissue homogenates, cell lysates and other biological fluids. |
Human Receptor Activator Of Nuclear Factor Kappa B (RANk) ELISA Kit |
|
RD-RANk-Hu-96T |
Reddot Biotech |
96T |
EUR 646.7 |
|
|
|
Description: tissue homogenates, cell lysates and other biological fluids. |
 ELISA Kit) Human RANκ (Receptor Activator of Nuclear Factor Kappa B) ELISA Kit |
|
EKE61301-5x96T |
Biomatik Corporation |
5x96T |
EUR 3124.08 |
Human RANκ (Receptor Activator of Nuclear Factor Kappa B) ELISA Kit |
|
EKE61301-96T |
Biomatik Corporation |
96T |
EUR 657.7 |
Taken collectively, our outcomes introduced that NS2A and NS4A critically antagonize MDA5/RIG-I-mediated NF-κB manufacturing and people proteins could appear to be managed in numerous mechanisms. This research might assist perceive the mechanisms how ZIKV controls innate immune responses and could also be supplied for improvement of ZIKV-specific medicines.
