Expanded and activated allogeneic NK cells are cytotoxic against B-chronic lymphocytic leukemia (B-CLL) cells with sporadic cases of resistance
December 10, 2020

Expanded and activated allogeneic NK cells are cytotoxic against B-chronic lymphocytic leukemia (B-CLL) cells with sporadic cases of resistance

By Charles

Adoptive switch of allogeneic pure killer (NK) cells is changing into a reputable immunotherapy for hematological malignancies. Within the current work, utilizing an optimized enlargement/activation protocol of human NK cells, we generate expanded NK cells (eNK) with elevated expression of CD56 and NKp44, whereas sustaining that of CD16. These eNK cells exerted important cytotoxicity towards cells from 34 B-CLL sufferers, with only one pattern exhibiting resistance. This sporadic resistance didn’t correlate with match between KIR ligands expressed by the eNK cells and the leukemic cells, whereas cells with match resulted delicate to eNK cells. This implies that KIR mismatch just isn’t related when expanded NK cells are used as effectors.

As well as, we discovered two examples of de novo resistance to eNK cell cytotoxicity through the scientific course of the illness. Resistance correlated with KIR-ligand match in one of many sufferers, however not within the different, and was related to a major enhance in PD-L1 expression within the cells from each sufferers. Remedy of one in every of these sufferers with idelalisib correlated with the lack of PD-L1 expression and with re-sensitization to eNK cytotoxicity. We confirmed the idelalisib-induced lower in PD-L1 expression within the B-CLL cell line Mec1 and in cultured cells from B-CLL sufferers. As a principal conclusion, our outcomes reinforce the feasibility of utilizing expanded and activated allogeneic NK cells within the remedy of B-CLL.

This text ready a simvastatin-NLCs for the remedy of arteriosclerotic occlusive illness of decrease limbs. Taking the dimensions distribution, polydispersity coefficient, encapsulation effectivity and drug loading of simvastatin-NLCs as analysis indicators, varied prescription elements of simvastatin- NLCs have been investigated. The in vitro launch conduct and stability of simvastatin-NLCs have been additionally investigated. A hyperlipidemia rat mannequin was established utilizing high-fat diets. SD rats fed extraordinary weight loss program have been set as regular management teams. 20 rats, 20 within the simvastatin group and 20 within the simvastatin nanocarrier group.

Pathogen-reduced PRP blocks T-cell activation, induces Treg cells, and promotes TGF-β expression by cDCs and monocytes in mice

Alloimmunization towards platelet-rich plasma (PRP) transfusions can result in problems resembling platelet refractoriness or rejection of subsequent transfusions and transplants. In mice, pathogen discount remedy of PRP with UVB mild and riboflavin (UV+R) prevents alloimmunization and seems to induce partial antigen-specific tolerance to subsequent transfusions. Herein, the in vivo responses of antigen-presenting cells and T cells to transfusion with UV+R-treated allogeneic PRP have been evaluated to grasp the mobile immune responses resulting in antigen-specific tolerance.
Mice that acquired UV+R-treated PRP had considerably elevated reworking progress issue β (TGF-β) expression by CD11b+ CD4+ CD11cHi standard dendritic cells (cDCs) and CD11bHi monocytes (P < .05). Whereas strong T-cell responses to transfusions with untreated allogeneic PRP have been noticed (P < .05), these have been blocked by UV+R remedy. Mice given UV+R-treated PRP adopted by untreated PRP confirmed an early important (P < .01) enrichment in regulatory T (Treg) cells and related TGF-β manufacturing in addition to diminished effector T-cell responses. Adoptive switch of T-cell-enriched splenocytes from mice given UV+R-treated PRP into naive recipients led to a small however important discount of CD8+ T-cell responses to subsequent allogeneic transfusion.
These knowledge reveal that pathogen discount with UV+R induces a tolerogenic profile by means of CD11b+ CD4+ cDCs, monocytes, and induction of Treg cells, blocking T-cell activation and lowering secondary T-cell responses to untreated platelets in vivo.
 Expanded and activated allogeneic NK cells are cytotoxic against B-chronic lymphocytic leukemia (B-CLL) cells with sporadic cases of resistance

Expanded and activated allogeneic NK cells are cytotoxic against B-chronic lymphocytic leukemia (B-CLL) cells with sporadic cases of resistance

Activation of 4-1BBL+ B cells with CD40 agonism and IFNγ elicits potent immunity towards glioblastoma

Immunotherapy has revolutionized the remedy of many tumors. Nevertheless, most glioblastoma (GBM) sufferers haven’t, thus far, benefited from such successes. With the purpose of exploring methods to spice up anti-GBM immunity, we developed a B cell-based vaccine (BVax) that consists of 4-1BBL+ B cells activated with CD40 agonism and IFNγ stimulation. BVax migrates to key secondary lymphoid organs and is proficient at antigen cross-presentation, which promotes each the survival and the performance of CD8+ T cells. A mix of radiation, BVax, and PD-L1 blockade conferred tumor eradication in 80% of handled tumor-bearing animals.
This remedy elicited immunological reminiscence that prevented the expansion of recent tumors upon subsequent reinjection in cured mice. GBM patient-derived BVax was profitable in activating autologous CD8+ T cells; these T cells confirmed a powerful capability to kill autologous glioma cells. Our research gives an environment friendly different to present immunotherapeutic approaches that may be readily translated to the clinic.  Lipocalin2 (Lcn2) has been proven to be an important regulator of tumorigenesis in a wide range of completely different cancers. Nevertheless, its expression patterns and doable roles in ovarian most cancers stay obscure. The purpose of this research was to analyze the expression of Lcn2 in ovarian most cancers cells and to find out any potential affiliation between Lcn2 and ovarian tumor growth and most cancers development.

Recombinant Human Glutathione S-transferase kappa 1 Protein, GST, E.coli-100ug

QP6125-ec-100ug 100ug
EUR 511.2

Glutathione S-Transferase kappa 1 (Recombinant)

20-abx073098
  • EUR 276.00
  • EUR 3433.20
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Glutathione S Transferase Kappa 1 (GSTK1) Antibody

20-abx215747
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

Glutathione S Transferase Kappa 1 (GSTk1) Antibody

20-abx103596
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Glutathione S Transferase Kappa 1 (GSTk1) Antibody

20-abx103597
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Glutathione S Transferase Kappa 1 (GSTk1) Antibody

20-abx103598
  • EUR 526.80
  • EUR 159.60
  • EUR 1479.60
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Glutathione S Transferase Kappa 1 (GSTK1) Antibody

20-abx304096
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Recombinant Glutathione S Transferase Kappa 1 (GSTk1)

4-RPB089Hu01
  • EUR 550.08
  • EUR 271.20
  • EUR 1732.80
  • EUR 657.60
  • EUR 1195.20
  • EUR 444.00
  • EUR 4152.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Glutathione S Transferase Kappa 1 expressed in: E.coli

Recombinant Glutathione S Transferase Kappa 1 (GSTk1)

4-RPB089Mu01
  • EUR 618.89
  • EUR 289.20
  • EUR 1990.85
  • EUR 743.62
  • EUR 1367.23
  • EUR 489.60
  • EUR 4797.12
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Glutathione S Transferase Kappa 1 expressed in: E.coli

Recombinant Glutathione S Transferase Kappa 1 (GSTk1)

4-RPB089Ra01
  • EUR 580.19
  • EUR 278.40
  • EUR 1845.70
  • EUR 695.23
  • EUR 1270.46
  • EUR 463.20
  • EUR 4434.24
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Glutathione S Transferase Kappa 1 expressed in: E.coli

Recombinant Human Glutathione S-Transferase Kappa 1

7-02890 10µg Ask for price

Recombinant Human Glutathione S-Transferase Kappa 1

7-02891 50µg Ask for price

Recombinant Human Glutathione S-Transferase Kappa 1

7-02892 1mg Ask for price

Glutathione S Transferase Kappa 1 (GSTk1) Antibody

20-abx172615
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Glutathione S Transferase Kappa 1 (GSTK1) Antibody

20-abx112775
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Glutathione S Transferase Kappa 1 (GSTK1) Antibody

20-abx004014
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Glutathione S Transferase Kappa 1 (GSTK1) Antibody

abx034548-400ul 400 ul
EUR 627.6

Glutathione S Transferase Kappa 1 (GSTK1) Antibody

abx034548-80l 80 µl
EUR 343.2

Glutathione S Transferase Kappa 1 (GSTk1) Antibody

20-abx270271
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Glutathione S Transferase Kappa 1 (GSTk1) Antibody

20-abx270272
  • EUR 560.40
  • EUR 644.40
  • EUR 326.40
  • EUR 978.00
  • EUR 427.20
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Glutathione S Transferase Kappa 1 (GSTK1) Antibody

20-abx322081
  • EUR 526.80
  • EUR 393.60
  • 100 ul
  • 50 ul

Human Glutathione S Transferase Kappa 1 (GSTk1) Protein

20-abx066841
  • EUR 777.60
  • EUR 326.40
  • EUR 2331.60
  • EUR 910.80
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Glutathione S Transferase Kappa 1 (GSTk1) Protein

20-abx066842
  • EUR 861.60
  • EUR 343.20
  • EUR 2682.00
  • EUR 1028.40
  • EUR 610.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Glutathione S Transferase Kappa 1 (GSTk1) Protein

20-abx066843
  • EUR 811.20
  • EUR 326.40
  • EUR 2481.60
  • EUR 961.20
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Glutathione S Transferase Kappa 1 (GSTK1) Antibody (HRP)

20-abx304097
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Glutathione S Transferase Kappa 1 (GSTK1) Antibody (FITC)

20-abx304098
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Glutathione S Transferase Kappa 1 (GSTK1) Antibody (Biotin)

20-abx304099
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Glutathione S-Transferase (GST) Antibody

abx018228-100ug 100 ug
EUR 460.8

Glutathione S-Transferase (GST) Antibody

abx019095-100ug 100 ug
EUR 410.4

Glutathione S-Transferase (GST) Antibody

abx019096-100ug 100 ug
EUR 410.4

Glutathione S-Transferase (GST) Antibody

abx019100-100ug 100 ug
EUR 385.2

Glutathione S-Transferase (GST) Antibody

abx020558-100ug 100 ug
EUR 1362

Glutathione S-Transferase (GST) Antibody

abx038445-100ug 100 ug
EUR 469.2

Glutathione S-Transferase (GST) Antibody

abx200555-100ug 100 ug
EUR 376.8

Glutathione S-Transferase (GST) Antibody

abx233683-100ug 100 ug
EUR 577.2

Glutathione S-Transferase (GST) Antibody

abx233684-100ug 100 ug
EUR 577.2

Glutathione S-Transferase (GST) Antibody

abx233685-100ug 100 ug
EUR 577.2

Glutathione S-Transferase

20-abx073083
  • EUR 276.00
  • EUR 3433.20
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

anti-Glutathione S Transferase theta 1

YF-PA23840 50 ul
EUR 400.8
Description: Mouse polyclonal to Glutathione S Transferase theta 1

anti-Microsomal Glutathione S-transferase 1

YF-PA24151 50 ul
EUR 400.8
Description: Mouse polyclonal to Microsomal Glutathione S-transferase 1

anti-glutathione S transferase Omega 1

YF-PA25340 50 ul
EUR 400.8
Description: Mouse polyclonal to glutathione S transferase Omega 1

anti-Microsomal Glutathione S-transferase 1

YF-PA13153 100 ug
EUR 483.6
Description: Rabbit polyclonal to Microsomal Glutathione S-transferase 1

anti-glutathione S transferase Omega 1

YF-PA16299 50 ul
EUR 435.6
Description: Mouse polyclonal to glutathione S transferase Omega 1

anti-glutathione S transferase Omega 1

YF-PA16300 50 ug
EUR 435.6
Description: Mouse polyclonal to glutathione S transferase Omega 1

anti-glutathione S transferase Omega 1

YF-PA16301 100 ug
EUR 483.6
Description: Rabbit polyclonal to glutathione S transferase Omega 1

Rabbit Anti-Glutathione Transferase, GST (S. japonicum, E. coli) antiserum # 1

GST11-S 100 ul
EUR 548.4

Recombinant Mouse Glutathione S-transferase P 1 Protein, His, Yeast-100ug

QP6126-ye-100ug 100ug
EUR 685.2

Glutathione S Transferase Omega 1 (GSTO1) Antibody

abx018054-100ug 100 ug
EUR 460.8

Glutathione S Transferase Omega 1 (GSTO1) Antibody

abx018055-100ug 100 ug
EUR 460.8

Glutathione S Transferase Mu 1 (GSTM1) Antibody

abx018209-100ug 100 ug
EUR 410.4

Glutathione S Transferase Alpha 1 (GSTA1) Antibody

abx233686-100ug 100 ug
EUR 577.2

Glutathione S Transferase Mu 1 (GSTM1) Antibody

abx233692-100ug 100 ug
EUR 610.8

Glutathione S Transferase Omega 1 (GSTO1) Antibody

abx233696-100ug 100 ug
EUR 577.2

Glutathione S Transferase Omega 1 (GSTO1) Antibody

abx233697-100ug 100 ug
EUR 661.2

Glutathione S Transferase Theta 1 (GSTT1) Antibody

abx233700-100ug 100 ug
EUR 577.2

Glutathione S Transferase Alpha 1 (GSTA1) Antibody

abx340021-100ug 100 ug
EUR 469.2

GSTM1 Antibody / Glutathione S-Transferase mu 1

V7280-100UG 100 ug
EUR 499
Description: Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, each of which are composed of proteins that have a variety of functions throughout the cell. The GSTM proteins (GSTM1-GSTM5 in human and GSTM1-GSTM7 in mouse) are members of the mu class of enzymes that conjugate with glutathione and function in the detoxification of carcinogens, environmental toxins and products of oxidative stress. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

GSTM1 Antibody / Glutathione S-Transferase mu 1

V7280SAF-100UG 100 ug
EUR 499
Description: Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, each of which are composed of proteins that have a variety of functions throughout the cell. The GSTM proteins (GSTM1-GSTM5 in human and GSTM1-GSTM7 in mouse) are members of the mu class of enzymes that conjugate with glutathione and function in the detoxification of carcinogens, environmental toxins and products of oxidative stress. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

anti-Glutathione S Transferase alpha

YF-PA12145 50 ul
EUR 435.6
Description: Mouse polyclonal to Glutathione S Transferase alpha

anti-Glutathione S Transferase alpha

YF-PA12146 50 ug
EUR 435.6
Description: Mouse polyclonal to Glutathione S Transferase alpha

anti-Glutathione S Transferase alpha

YF-PA12147 100 ul
EUR 483.6
Description: Rabbit polyclonal to Glutathione S Transferase alpha

anti-Glutathione S Transferase alpha

YF-PA12148 100 ug
EUR 483.6
Description: Rabbit polyclonal to Glutathione S Transferase alpha

Human GSTκ1(Glutathione S Transferase Kappa 1) ELISA Kit

EH3195 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human Glutathione S Transferase Kappa 1 (GSTκ1) CLIA Kit

abx197034-96tests 96 tests
EUR 990

Chicken Glutathione S Transferase Kappa 1 (GSTK1) ELISA Kit

abx356429-96tests 96 tests
EUR 990

Rabbit Glutathione S Transferase Kappa 1 (GSTK1) ELISA Kit

abx362448-96tests 96 tests
EUR 990

Monkey Glutathione S Transferase Kappa 1 (GSTK1) ELISA Kit

abx359631-96tests 96 tests
EUR 990

Pig Glutathione S Transferase Kappa 1 (GSTK1) ELISA Kit

abx361508-96tests 96 tests
EUR 990

Human Glutathione S Transferase Kappa 1 (GSTk1) ELISA Kit

abx574073-96tests 96 tests
EUR 943.2

Human Glutathione S Transferase Kappa 1 (GSTΚ1) ELISA Kit

abx252596-96tests 96 tests
EUR 764.4

Mouse Glutathione S- transferase kappa 1, Gstk1 ELISA KIT

ELI-31340m 96 Tests
EUR 1038

Human Glutathione S- transferase kappa 1, GSTK1 ELISA KIT

ELI-31574h 96 Tests
EUR 988.8

Glutathione S Transferase Kappa 1 (GSTk1) Polyclonal Antibody (Human)

4-PAB089Hu01
  • EUR 286.80
  • EUR 2869.20
  • EUR 717.60
  • EUR 358.80
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glutathione S Transferase Kappa 1 (GSTk1)

GSTK1 Glutathione S-Transferase Kappa 1 Human Recombinant Protein

PROTQ9Y2Q3 Regular: 50ug
EUR 380.4
Description: GSTK1 Human Recombinant produced in E.Coli is a single, non-glycosylated,_x000D_ polypeptide chain containing 226 amino acids (1-226 a.a.) and having a molecular mass of 25.5 kDa. _x000D_ GSTK1 is purified by proprietary chromatographic techniques._x000D_

Glutathione-S-transferase Antibody

20-abx137109
  • EUR 627.60
  • EUR 1128.00
  • EUR 427.20
  • 0.2 mg
  • 0.5 mg
  • 100 ug

Recombinant Human Glutathione S-transferase A2 Protein, GST, E.coli-100ug

QP6123-ec-100ug 100ug
EUR 685.2

Recombinant Rat Glutathione S-transferase P Protein, His, E.coli-100ug

QP6127-ec-100ug 100ug
EUR 685.2

Blattella germanica Glutathione S-transferase

1-CSB-YP522732BTL
  • EUR 814.80
  • EUR 402.00
  • EUR 2606.40
  • EUR 1261.20
  • EUR 1730.40
  • EUR 522.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Blattella germanica Glutathione S-transferase expressed in Yeast

Blattella germanica Glutathione S-transferase

1-CSB-EP522732BTL
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Blattella germanica Glutathione S-transferase expressed in E.coli

Glutathione S-Transferase P (GSTP1) Antibody

abx015880-100ug 100 ug
EUR 493.2

Glutathione S-Transferase A2 (GSTA2) Antibody

abx233687-100ug 100 ug
EUR 577.2

Glutathione S-Transferase P (GSTP1) Antibody

abx233699-100ug 100 ug
EUR 577.2

Glutathione S-Transferase P (GSTP1) Antibody

abx340197-100ug 100 ug
EUR 469.2

Glutathione S-Transferase A2 (GSTA2) Antibody

abx340200-100ug 100 ug
EUR 469.2

Recombinant Mouse Glutathione S-transferase P 1 Protein, His-SUMO, E.coli-100ug

QP6126-ec-100ug 100ug
EUR 685.2

Anti-glutathione S transferase Omega 1 (3D9)

YF-MA16835 100 ug
EUR 435.6
Description: Mouse monoclonal to glutathione S transferase Omega 1

Anti-glutathione S transferase Omega 1 (1B6)

YF-MA16836 100 ug
EUR 435.6
Description: Mouse monoclonal to glutathione S transferase Omega 1

Rat Glutathione S-transferase alpha-1 (Gsta1)

1-CSB-EP009970RA
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Rat Glutathione S-transferase alpha-1(Gsta1) expressed in E.coli

Mouse Glutathione S-transferase P 1 (Gstp1)

1-CSB-EP009989MO
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Glutathione S-transferase P 1(Gstp1) expressed in E.coli

Mouse Glutathione S-transferase P 1 (Gstp1)

1-CSB-YP009989MO
  • EUR 604.80
  • EUR 318.00
  • EUR 2198.40
  • EUR 915.60
  • EUR 1459.20
  • EUR 400.80
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Glutathione S-transferase P 1(Gstp1) expressed in Yeast

Glutathione S Transferase Kappa 1 (GSTk1) Polyclonal Antibody (Human), APC

4-PAB089Hu01-APC
  • EUR 399.60
  • EUR 3735.60
  • EUR 1046.40
  • EUR 507.60
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glutathione S Transferase Kappa 1 (GSTk1). This antibody is labeled with APC.

Glutathione S Transferase Kappa 1 (GSTk1) Polyclonal Antibody (Human), Biotinylated

4-PAB089Hu01-Biotin
  • EUR 363.60
  • EUR 2809.20
  • EUR 836.40
  • EUR 442.80
  • EUR 259.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glutathione S Transferase Kappa 1 (GSTk1). This antibody is labeled with Biotin.

Glutathione S Transferase Kappa 1 (GSTk1) Polyclonal Antibody (Human), Cy3

4-PAB089Hu01-Cy3
  • EUR 483.60
  • EUR 4930.80
  • EUR 1345.20
  • EUR 627.60
  • EUR 294.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glutathione S Transferase Kappa 1 (GSTk1). This antibody is labeled with Cy3.

Glutathione S Transferase Kappa 1 (GSTk1) Polyclonal Antibody (Human), FITC

4-PAB089Hu01-FITC
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glutathione S Transferase Kappa 1 (GSTk1). This antibody is labeled with FITC.

Glutathione S Transferase Kappa 1 (GSTk1) Polyclonal Antibody (Human), HRP

4-PAB089Hu01-HRP
  • EUR 366.00
  • EUR 3256.80
  • EUR 926.40
  • EUR 459.60
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glutathione S Transferase Kappa 1 (GSTk1). This antibody is labeled with HRP.

Glutathione S Transferase Kappa 1 (GSTk1) Polyclonal Antibody (Human), PE

4-PAB089Hu01-PE
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glutathione S Transferase Kappa 1 (GSTk1). This antibody is labeled with PE.

Glutathione S Transferase Kappa 1 (GSTk1) Polyclonal Antibody (Human, Mouse)

4-PAB089Mu01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Glutathione S Transferase Kappa 1 (GSTk1)

Recombinant Glutathione S-Transferase

7-02872 10µg Ask for price

Recombinant Glutathione S-Transferase

7-02873 50µg Ask for price

Recombinant Glutathione S-Transferase

7-02874 1mg Ask for price

Glutathione S-Transferase (Recombinant)

20-abx073059
  • EUR 276.00
  • EUR 2798.40
  • EUR 393.60
  • 10 ug
  • 1 mg
  • 50 ug

Recombinant Human Glutathione S-transferase A4 Protein, His-SUMO, E.coli-100ug

QP6124-ec-100ug 100ug
EUR 489.6

Glutathione S-Transferase (GST) Antibody

20-abx210092
  • EUR 393.60
  • EUR 326.40
  • 100 ug
  • 50 ug

anti-Glutathione S Transferase theta 2

YF-PA23841 50 ul
EUR 400.8
Description: Mouse polyclonal to Glutathione S Transferase theta 2

anti-Glutathione S Transferase theta 2

YF-PA12166 50 ug
EUR 435.6
Description: Mouse polyclonal to Glutathione S Transferase theta 2

anti-Glutathione S Transferase theta 2

YF-PA12167 100 ug
EUR 483.6
Description: Rabbit polyclonal to Glutathione S Transferase theta 2

Anti-Glutathione S Transferase alpha (2F7)

YF-MA13344 100 ug
EUR 435.6
Description: Mouse monoclonal to Glutathione S Transferase alpha

Anti-Glutathione S Transferase alpha (1F9)

YF-MA13345 100 ug
EUR 435.6
Description: Mouse monoclonal to Glutathione S Transferase alpha

Glutathione-S-transferase (GST) Antibody

20-abx137496
  • EUR 844.80
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 20 ug
  • 5 ug

ELISA kit for Human GST?1 (Glutathione S Transferase Kappa 1)

E-EL-H1402 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human GST?1 (Glutathione S Transferase Kappa 1) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Human GST?1 (Glutathione S Transferase Kappa 1)

E-CL-H0907 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human GST?1 (Glutathione S Transferase Kappa 1) in samples from Serum, Plasma, Cell supernatant

Glutathione S Transferase Mu 2 (GSTM2) Antibody

abx117065-100ug 100 ug
EUR 560.4

Glutathione S Transferase Alpha 3 (GSTA3) Antibody

abx018208-100ug 100 ug
EUR 410.4

Glutathione S Transferase Mu 4 (GSTM4) Antibody

abx037726-100ug 100 ug
EUR 469.2

Glutathione S Transferase Theta 2 (GSTT2) Antibody

abx036117-100ug 100 ug
EUR 469.2

Glutathione S Transferase Mu 3 (GSTM3) Antibody

abx036297-100ug 100 ug
EUR 469.2

Glutathione S Transferase Alpha 4 (GSTA4) Antibody

abx036478-100ug 100 ug
EUR 469.2

Glutathione S Transferase Alpha 3 (GSTA3) Antibody

abx233688-100ug 100 ug
EUR 577.2

Glutathione S Transferase Alpha 4 (GSTA4) Antibody

abx233689-100ug 100 ug
EUR 661.2

Glutathione S Transferase Mu 3 (GSTM3) Antibody

abx233693-100ug 100 ug
EUR 610.8

Glutathione S Transferase Mu 4 (GSTM4) Antibody

abx233694-100ug 100 ug
EUR 577.2

Glutathione S Transferase Mu 5 (GSTM5) Antibody

abx233695-100ug 100 ug
EUR 577.2

Glutathione S Transferase Omega 2 (GSTO2) Antibody

abx233698-100ug 100 ug
EUR 610.8

Glutathione S Transferase Theta 2 (GSTT2) Antibody

abx233701-100ug 100 ug
EUR 577.2

Glutathione S Transferase Theta 2B (GSTT2B) Antibody

abx233702-100ug 100 ug
EUR 610.8

Glutathione S Transferase Mu 5 (GSTM5) Antibody

abx340198-100ug 100 ug
EUR 469.2

Glutathione S Transferase Mu 2 (GSTM2) Antibody

abx340199-100ug 100 ug
EUR 469.2

GSTM4 Antibody / Glutathione S-Transferase mu 4

R36474-100UG 100 ug
EUR 399

GSTM3 Antibody / Glutathione S-Transferase mu 3

R36475-100UG 100 ug
EUR 399

GSTM3 Antibody / Glutathione S-Transferase mu 3

V7281-100UG 100 ug
EUR 499
Description: Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, each of which are composed of proteins that have a variety of functions throughout the cell. The GSTM proteins (GSTM1-GSTM5 in human and GSTM1-GSTM7 in mouse) are members of the mu class of enzymes that conjugate with glutathione and function in the detoxification of carcinogens, environmental toxins and products of oxidative stress. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. GSTM3 protein is selectively expressed in the testis and brain. GSTM3 may also be tumor suppressive in RCC, as low expression has been demonstrated to correlate with RCC risk and poor prognosis in post-op patients.

GSTM3 Antibody / Glutathione S-Transferase mu 3

V7281SAF-100UG 100 ug
EUR 499
Description: Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, each of which are composed of proteins that have a variety of functions throughout the cell. The GSTM proteins (GSTM1-GSTM5 in human and GSTM1-GSTM7 in mouse) are members of the mu class of enzymes that conjugate with glutathione and function in the detoxification of carcinogens, environmental toxins and products of oxidative stress. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. GSTM3 protein is selectively expressed in the testis and brain. GSTM3 may also be tumor suppressive in RCC, as low expression has been demonstrated to correlate with RCC risk and poor prognosis in post-op patients.

GSTM2 Antibody / Glutathione S-Transferase mu 2

V7416-100UG 100 ug
EUR 499
Description: Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, each of which are composed of proteins that have a variety of functions throughout the cell. The GSTM proteins (GSTM1-GSTM5 in human and GSTM1-GSTM7 in mouse) are members of the mu class of enzymes that conjugate with glutathione and function in the detoxification of carcinogens, environmental toxins and products of oxidative stress. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. GSTM2 is specific for muscle hence the alternate name GST muscle antibody.
Our outcomes indicated that Lcn2 was upregulated in tumor tissue from ovarian most cancers sufferers in addition to in three ovarian most cancers cell traces in comparison with regular tissues and cells. Overexpression of Lcn2 promoted each cell proliferation and migration in ovarian most cancers cells. Conversely, knockdown of Lcn2 in cell traces suppressed each migration and proliferation.