Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling
Introduction and targets: The activation of hepatic stellate cells (HSCs) is the primary reason for liver fibrosis. The useful results of fibroblast development issue (FGF) 19 on liver fibrosis had been not too long ago reported. The S. miltiorrhiza in addition to S. miltiorrhiza derived bioactive chemical parts has proven distinguished antifibrotic results in liver fibrosis however the mechanism continues to be not totally understood. We aimed to research the bioactive compounds derived from S. miltiorrhiza which exerts antifibrotic results in HSCs through regulating FGF19.
Supplies and strategies: FGF19 stage in tradition media was decided by enzyme-linked immunosorbent assay. Cell proliferation was measured by Cell Counting Package-Eight assay. Additional, mRNA and protein expressions had been assessed by quantitative polymerase chain response and western blotting, respectively. Pulling down of FGF receptor 4 (FGFR4) by transfection with siRNA was used to substantiate the function of FGF19/FGFR4 signaling.
Outcomes: Utilizing the human HSC cell line LX-2, we screened a number of pure merchandise and located that bioactive compounds remoted from Salvia miltiorrhiza, notably salvianolic acid B, strongly upregulated FGF19 secretion by LX-2 cells. We additional confirmed that salvianolic acid B inhibited lipopolysaccharide (LPS)-induced HSC proliferation and activation. LPS remedy might also cut back the mRNA and protein ranges of FGF19 and its receptor FGFR4. Salvianolic acid B remedy restored the impaired expressions of FGF19 and FGFR4. Lastly, FGFR4 knockdown abolished the antifibrotic results of salvianolic acid B within the LPS-induced HSC activation mannequin.
Conclusions: Salvianolic acid B prevented LPS-induced HSC proliferation and activation by enhancing antifibrotic FGF19/FGFR4 signaling.

Glutaredoxin deficiency promotes activation of the reworking development issue beta pathway in airway epithelial cells, in affiliation with fibrotic airway transforming

S-glutathionylation of reactive protein cysteines is a post-translational occasion that performs a important function in transducing indicators from oxidants into organic responses. S-glutathionylation might be reversed by the deglutathionylating enzyme glutaredoxin (GLRX). Now we have beforehand demonstrated that ablation of Glrx sensitizes mice to the event of parenchymal lung fibrosis(1). It stays unclear whether or not GLRX additionally controls airway fibrosis, a scientific function related to bronchial asthma and continual obstructive pulmonary illness, and whether or not GLRX controls the biology of airway epithelial cells, which have been implicated within the pathophysiology of those ailments.
Within the current examine we utilized a home mud mite (HDM) mannequin of allergic airway illness in wild sort (WT) and Glrx-/- mice on a C57BL/6 background susceptible to develop airway fibrosis, and tracheal basal stem cells derived from WT mice, international Glrx-/- mice, or bi-transgenic mice permitting conditional ablation of the Glrx gene. Herein we present that absence of Glrx led to enhanced HDM-induced collagen deposition, elevated ranges of reworking development issue beta 1 (TGFB1) within the bronchoalveolar lavage, and resulted in will increase in airway hyperresponsiveness. Airway epithelial cells remoted from Glrx-/- mice or following conditional ablation of Glrx confirmed spontaneous will increase in secretion of TGFB1. Glrx-/- basal cells additionally confirmed spontaneous TGFB pathway activation, in affiliation with elevated expression of mesenchymal genes, together with collagen 1a1 and fibronectin. Total, these findings counsel that GLRX regulates airway fibrosis through a mechanism(s) that contain the plasticity of basal cells, the stem cells of the airways.
The outbreak of the 2019 coronavirus illness (named, COVID‑19), brought on by the novel SARS‑CoV‑2 virus, represents a worldwide extreme risk to public well being. It’s of the utmost significance to characterize the immune responses towards the SARS‑CoV‑2 and the mechanisms of hyperinflammation, to be able to design higher therapeutic methods for COVID‑19. Within the current examine, a transcriptomic evaluation was carried out to profile the immune signatures in lung and the bronchoalveolar lavage fluid samples from COVID‑19 sufferers and controls. Our information concordantly revealed elevated humoral responses to an infection. The elucidation of the host responses to SARS‑CoV‑2 an infection could additional enhance our understanding of COVID‑19 pathogenesis and counsel higher therapeutic methods.
 Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling

Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling

Analysis of Bcell intracellular signaling by monitoring the PI3K-Akt axis in sufferers with frequent variable immunodeficiency and activated phosphoinositide 3-kinase delta syndrome

Background: Major antibody deficiencies (PADs) are characterised by hypogammaglobulinemia and impaired B-cell differentiation. Sufferers with frequent variable immunodeficiency (CVID) current extreme reductions in not less than 2 serum immunoglobulins and impaired terminal differentiation of B cells. Most sufferers with CVID don’t seem to current monogenic defects. Activated phosphoinositide 3-kinase delta syndrome (APDS), brought on by gain-of-function mutations within the PIK3CD gene (p110δ), can current in sufferers with a CVID-like phenotype. Reminiscence B-cell differentiation requires the orchestrated activation of quite a few intracellular signaling pathways, which promote transcriptional packages required for long-term B-cell survival. The goal of this examine was to develop a circulation cytometry assay to hint the PI3K-Akt-mTOR pathway, a important part of B-cell homeostasis, and analyze its standing in PADs.
Strategies: We analyzed the intracellular expression of Akt and S6 by circulation cytometry and their phosphorylation standing in each baseline circumstances and upon B-cell receptor activation with anti-IgM in numerous main B-cell subsets of sufferers with CVID and APDS.
Outcomes: B cells from CVID sufferers confirmed decreased phosphorylation in Akt and S6 proteins after anti-IgM stimulation. Constitutive excessive baseline B-cell ranges of Akt and S6 phosphorylation in a affected person with APDS had been decreased as soon as m-TOR inhibition remedy was initiated.

Immunoglobulin Kappa (Igk) Antibody

abx176921-1096tests 10 × 96 tests
EUR 750

Immunoglobulin Kappa (Igk) Antibody

abx176921-596tests 5 × 96 tests
EUR 337.5

Immunoglobulin Kappa (Igk) Antibody

abx176921-96tests 96 tests
EUR 275

Immunoglobulin Kappa (Igk) Antibody

abx176923-1096tests 10 × 96 tests
EUR 825

Immunoglobulin Kappa (Igk) Antibody

abx176923-596tests 5 × 96 tests
EUR 362.5

Immunoglobulin Kappa (Igk) Antibody

abx176923-96tests 96 tests
EUR 287.5

Immunoglobulin Kappa (Igk) Antibody

abx270090-1ml 1 ml
EUR 412.5

Immunoglobulin Kappa (Igk) Antibody

abx270090-200l 200 µl
EUR 300

Immunoglobulin Kappa (Igk) Antibody

abx132190-01mg 0.1 mg
EUR 275

Immunoglobulin Kappa Light Chain (Ig kappa LC) Antibody

abx137077-01mg 0.1 mg
EUR 487.5

Mouse Immunoglobulin M Kappa (IgM Kappa) Protein

abx670294-1mg 1 mg
EUR 760.8

Mouse Immunoglobulin E Kappa (IgE Kappa) Protein

abx670299-05mg 0.5 mg
EUR 727.2

Mouse Immunoglobulin M Kappa (IgM Kappa) Protein

abx670294-100g 100 µg
EUR 637.5

Mouse Immunoglobulin E Kappa (IgE Kappa) Protein

abx670299-100g 100 µg
EUR 512.5

Human Immunoglobulin G1 Kappa (IgG1 Kappa) Protein

abx670165-1mg 1 mg
EUR 560.4

Human Immunoglobulin G2 Kappa (IgG2 Kappa) Protein

abx670166-1mg 1 mg
EUR 627.6

Mouse Immunoglobulin G1 Kappa (IgG1 Kappa) Protein

abx670291-1mg 1 mg
EUR 760.8

Mouse Immunoglobulin G1 Kappa (IgG1 Kappa) Protein

abx670291-100g 100 µg
EUR 700

Immunoglobulin Kappa (Igk) Antibody (PE)

20-abx270852
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  • 100 tests
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Immunoglobulin Kappa (Igk) Antibody (PE)

20-abx274585
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  • 100 ug
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Immunoglobulin Kappa (Igk) Antibody (PE)

abx270852-1ml 1 ml
EUR 1212.5

Immunoglobulin Kappa (Igk) Antibody (PE)

abx270852-200l 200 µl
EUR 737.5

Immunoglobulin kappa Protein (OVA)

20-abx165553
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  • 100 ug
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Immunoglobulin Kappa (Igk) Antibody (APC)

20-abx270620
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  • 100 tests
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Immunoglobulin Kappa (Igk) Antibody (APC)

20-abx274586
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  • 100 ug
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Immunoglobulin Kappa (Igk) Antibody (APC)

abx270620-1ml 1 ml
EUR 1437.5

Immunoglobulin Kappa (Igk) Antibody (APC)

abx270620-200l 200 µl
EUR 875

Immunoglobulin Kappa (Igk) Antibody (FITC)

20-abx270388
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  • 100 tests
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Immunoglobulin Kappa (Igk) Antibody Pair

20-abx370695
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  • 10 × 96 tests
  • 5 × 96 tests

Immunoglobulin Kappa (Igk) Antibody (FITC)

abx270388-1ml 1 ml
EUR 1000

Immunoglobulin Kappa (Igk) Antibody (FITC)

abx270388-200l 200 µl
EUR 612.5

Immunoglobulin Kappa (Igk) Antibody Pair

abx370695-100g 100 µg
EUR 2425

Immunoglobulin Kappa (Igk) Antibody Pair

abx370695-50g 50 µg
EUR 1487.5

Immunoglobulin Kappa (Igk) Antibody (APC/Cy7)

20-abx274584
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  • 100 ug
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Immunoglobulin kappa constant (IGKC) Antibody

abx343593-100l 100 µl
EUR 250

Immunoglobulin kappa constant (IGKC) Antibody

abx343593-50l 50 µl
EUR 162.5

Mouse Immunoglobulin M Kappa (IgM) Antibody

20511-05011 150 ug
EUR 175

Mouse Immunoglobulin G2a Kappa (IgG2a Kappa) Protein

abx670292-1mg 1 mg
EUR 760.8

Mouse Immunoglobulin G2b Kappa (IgG2b Kappa) Protein

abx670293-1mg 1 mg
EUR 760.8

Mouse Immunoglobulin G2a Kappa (IgG2a Kappa) Protein

abx670292-100g 100 µg
EUR 612.5

Mouse Immunoglobulin G2b Kappa (IgG2b Kappa) Protein

abx670293-50g 50 µg
EUR 587.5

Immunoglobulin Kappa (Igk) Polyclonal Antibody

CAU31617-100ul 100ul
EUR 258.2

Immunoglobulin Kappa (Igk) Polyclonal Antibody

CAU31617-200ul 200ul
EUR 322.6

Immunoglobulin Kappa (Igk) Polyclonal Antibody

CAU29980-100ul 100ul
EUR 241.9

Immunoglobulin Kappa (Igk) Polyclonal Antibody

CAU29980-200ul 200ul
EUR 302.4

Mouse Immunoglobulin kappa Peptide (OVA)

abx165553-100g 100 µg
EUR 2062.5

Mouse Immunoglobulin kappa Peptide (OVA)

abx165553-10g 10 µg
EUR 537.5

Mouse Immunoglobulin kappa Peptide (OVA)

abx165553-50g 50 µg
EUR 637.5

OVA Conjugated Immunoglobulin Kappa (Igk)

CPD038Hu21 10ug
EUR 138

OVA Conjugated Immunoglobulin Kappa (Igk)

4-CPD038Hu21
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Description: Recombinant Human Immunoglobulin Kappa expressed in: Protein conjugation

OVA Conjugated Immunoglobulin Kappa (Igk)

CPD038Mu21 10ug
EUR 160

OVA Conjugated Immunoglobulin Kappa (Igk)

4-CPD038Mu21
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  • 100 ug
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Description: Recombinant Mouse Immunoglobulin Kappa expressed in: chemical synthesis

OVA Conjugated Immunoglobulin Kappa (Igk)

RPU55072-100ug 100ug
EUR 426.8

OVA Conjugated Immunoglobulin Kappa (Igk)

RPU55072-1mg 1mg
EUR 1888.9

OVA Conjugated Immunoglobulin Kappa (Igk)

RPU55072-50ug 50ug
EUR 332.2

OVA Conjugated Immunoglobulin Kappa (Igk)

RPU51657-100ug 100ug
EUR 492.8

OVA Conjugated Immunoglobulin Kappa (Igk)

RPU51657-1mg 1mg
EUR 2184

OVA Conjugated Immunoglobulin Kappa (Igk)

RPU51657-50ug 50ug
EUR 384

ELISA Kit for Immunoglobulin Kappa (Igk)

SED038Hu 96Т
EUR 700

ELISA Kit for Immunoglobulin Kappa (Igk)

SED038Mu 96Т
EUR 720

Human Immunoglobulin Kappa (Igk) CLIA Kit

20-abx494060
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  • 10 × 96 tests
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  • 96 tests

Mouse Immunoglobulin Kappa (Igk) CLIA Kit

20-abx496452
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  • 10 × 96 tests
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  • 96 tests

Immunoglobulin Kappa Light Chain (IGKC) Antibody

abx227081-100g 100 µg
EUR 250

Immunoglobulin Kappa Light Chain (IGKC) Antibody

abx227082-100g 100 µg
EUR 250

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

20-abx258908
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  • 10 × 96 tests
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  • 96 tests

Human Immunoglobulin Kappa (Igk) ELISA Kit

20-abx156942
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Immunoglobulin Kappa (Igk) ELISA Kit

EKU09146-48T 48T
EUR 555.66

Human Immunoglobulin Kappa (Igk) ELISA Kit

EKU09146-5x96T 5x96T
EUR 3770.55

Human Immunoglobulin Kappa (Igk) ELISA Kit

EKU09146-96T 96T
EUR 793.8

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

EKU10997-48T 48T
EUR 571.55

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

EKU10997-5x96T 5x96T
EUR 3878.38

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

EKU10997-96T 96T
EUR 816.5

Human Immunoglobulin Kappa (Igk) ELISA Kit

EKN50257-48T 48T
EUR 345.73

Human Immunoglobulin Kappa (Igk) ELISA Kit

EKN50257-5x96T 5x96T
EUR 2346.03

Human Immunoglobulin Kappa (Igk) ELISA Kit

EKN50257-96T 96T
EUR 493.9

Mouse Igk(Immunoglobulin Kappa) ELISA Kit

ELK7759-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse Igk. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse Igk. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse Igk, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse Igk in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse Igk(Immunoglobulin Kappa) ELISA Kit

ELK7759-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse Igk. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse Igk. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse Igk, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse Igk in the samples is then determined by comparing the OD of the samples to the standard curve.

Human Igk(Immunoglobulin Kappa) ELISA Kit

ELK5262-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Igk. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Igk. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human Igk, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Igk in the samples is then determined by comparing the OD of the samples to the standard curve.

Human Igk(Immunoglobulin Kappa) ELISA Kit

ELK5262-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Igk. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Igk. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human Igk, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Igk in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

EKN52108-48T 48T
EUR 355.6

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

EKN52108-5x96T 5x96T
EUR 2413

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

EKN52108-96T 96T
EUR 508

Human Immunoglobulin Kappa(Igk)ELISA Kit

QY-E02169 96T
EUR 433.2

Human Immunoglobulin Kappa (Igk) ELISA Kit

SED038Hu-10x96wellstestplate 10x96-wells test plate
EUR 5677.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immunoglobulin Kappa (Igk) in serum, plasma and other biological fluids.

Human Immunoglobulin Kappa (Igk) ELISA Kit

SED038Hu-1x48wellstestplate 1x48-wells test plate
EUR 572.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immunoglobulin Kappa (Igk) in serum, plasma and other biological fluids.

Human Immunoglobulin Kappa (Igk) ELISA Kit

SED038Hu-1x96wellstestplate 1x96-wells test plate
EUR 766.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immunoglobulin Kappa (Igk) in serum, plasma and other biological fluids.

Human Immunoglobulin Kappa (Igk) ELISA Kit

SED038Hu-5x96wellstestplate 5x96-wells test plate
EUR 3090.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immunoglobulin Kappa (Igk) in serum, plasma and other biological fluids.

Human Immunoglobulin Kappa (Igk) ELISA Kit

4-SED038Hu
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Immunoglobulin Kappa (Igk) in samples from Serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

SED038Mu-10x96wellstestplate 10x96-wells test plate
EUR 5834.88
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immunoglobulin Kappa (Igk) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

SED038Mu-1x48wellstestplate 1x48-wells test plate
EUR 585.7
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immunoglobulin Kappa (Igk) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

SED038Mu-1x96wellstestplate 1x96-wells test plate
EUR 785.28
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immunoglobulin Kappa (Igk) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

SED038Mu-5x96wellstestplate 5x96-wells test plate
EUR 3173.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immunoglobulin Kappa (Igk) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

4-SED038Mu
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  • 10 plates of 96 wells
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  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Immunoglobulin Kappa (Igk) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Immunoglobulin Kappa (Igk) ELISA Kit

abx156942-100g 100 µg
EUR 6187.5

Human Immunoglobulin Kappa (Igk) ELISA Kit

abx156942-10g 10 µg
EUR 687.5

Human Immunoglobulin Kappa (Igk) ELISA Kit

abx156942-50g 50 µg
EUR 3275

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

abx258908-1mg 1 mg
EUR 6187.5

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

abx258908-20g 20 µg
EUR 3275

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

abx258908-5g 5 µg
EUR 687.5

Polyclonal Antibody to Immunoglobulin Kappa (Igk)

PAD038Hu01 100ul
EUR 245

Polyclonal Antibody to Immunoglobulin Kappa (Igk)

PAD038Mu08 100ul
EUR 252

Immunoglobulin kappa constant (IGKC) Antibody (HRP)

abx343594-100l 100 µl
EUR 250

Immunoglobulin kappa constant (IGKC) Antibody (HRP)

abx343594-50l 50 µl
EUR 162.5

Immunoglobulin kappa constant (IGKC) Antibody (FITC)

abx343595-100l 100 µl
EUR 250

Immunoglobulin kappa constant (IGKC) Antibody (FITC)

abx343595-50l 50 µl
EUR 162.5

Human Immunoglobulin Kappa (Igk) Protein (OVA)

20-abx651861
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  • 100 ug
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Human Immunoglobulin Kappa (Igk) Peptide (OVA)

abx651861-100g 100 µg
EUR 1787.5

Human Immunoglobulin Kappa (Igk) Peptide (OVA)

abx651861-10g 10 µg
EUR 475

Human Immunoglobulin Kappa (Igk) Peptide (OVA)

abx651861-50g 50 µg
EUR 562.5

Immunoglobulin Kappa (Igk) Polyclonal Antibody (Mouse)

4-PAD038Mu08
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  • 100ul
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  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin Kappa (Igk)

Immunoglobulin kappa constant (IGKC) Antibody (Biotin)

abx343596-100l 100 µl
EUR 250

Immunoglobulin kappa constant (IGKC) Antibody (Biotin)

abx343596-50l 50 µl
EUR 162.5

ELISA kit for Mouse Igk (Immunoglobulin Kappa)

ELK7759 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Immunoglobulin Kappa from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Human Igk (Immunoglobulin Kappa)

ELK5262 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Immunoglobulin Kappa from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Immunoglobulin Kappa (Igk) Polyclonal Antibody (Mouse), PE

4-PAD038Mu08-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin Kappa (Igk). This antibody is labeled with PE.

Immunoglobulin Kappa (Igk) Polyclonal Antibody (Mouse), APC

4-PAD038Mu08-APC
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  • 100ul
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  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin Kappa (Igk). This antibody is labeled with APC.

Immunoglobulin Kappa (Igk) Polyclonal Antibody (Mouse), Cy3

4-PAD038Mu08-Cy3
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  • 100ul
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Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin Kappa (Igk). This antibody is labeled with Cy3.

Immunoglobulin Kappa (Igk) Polyclonal Antibody (Mouse), HRP

4-PAD038Mu08-HRP
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  • 100ul
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  • 200ul
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Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin Kappa (Igk). This antibody is labeled with HRP.

Immunoglobulin Kappa Variable 1-5 (IGKV1-5) Antibody

20-abx113111
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  • 150 ul
  • 50 ul

Immunoglobulin Kappa Variable 1-5 (IGKV1-5) Antibody

abx234188-100ug 100 ug
EUR 610.8

Immunoglobulin Kappa Variable 1-5 (IGKV1-5) Antibody

abx113111-100l 100 µl
EUR 612.5

Immunoglobulin Kappa Variable 1-5 (IGKV1-5) Antibody

abx234188-100g 100 µg
EUR 350

Immunoglobulin Kappa (Igk) Polyclonal Antibody (Mouse), FITC

4-PAD038Mu08-FITC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin Kappa (Igk). This antibody is labeled with FITC.

Immunoglobulin Kappa (Igk) Magnetic Luminex Assay Kit

LKU607576-96T 96T
EUR 966

Immunoglobulin Kappa (Igk) Magnetic Luminex Assay Kit

LKU607578-96T 96T
EUR 993.6

Rat Kappa immunoglobulin light chain ELISA kit

E02K0067-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Kappa immunoglobulin light chain ELISA kit

E02K0067-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Kappa immunoglobulin light chain ELISA kit

E02K0067-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Kappa immunoglobulin light chain ELISA kit

E07K0067-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Kappa immunoglobulin light chain ELISA kit

E07K0067-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Kappa immunoglobulin light chain ELISA kit

E07K0067-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Kappa immunoglobulin light chain ELISA kit

E08K0067-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Kappa immunoglobulin light chain ELISA kit

E08K0067-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Conclusions: Intracellular circulation cytometry might be routinely employed to discover alterations within the PI3K-Akt-mTOR pathway in B cells from sufferers with PADs. AKT and S6 phosphorylation ranges are informative biomarkers that may very well be employed as mTOR inhibitors for monitoring therapies focusing on this pathway.