Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling
Introduction and targets: The activation of hepatic stellate cells (HSCs) is the primary reason for liver fibrosis. The useful results of fibroblast development issue (FGF) 19 on liver fibrosis had been not too long ago reported. The S. miltiorrhiza in addition to S. miltiorrhiza derived bioactive chemical parts has proven distinguished antifibrotic results in liver fibrosis however the mechanism continues to be not totally understood. We aimed to research the bioactive compounds derived from S. miltiorrhiza which exerts antifibrotic results in HSCs through regulating FGF19.
Supplies and strategies: FGF19 stage in tradition media was decided by enzyme-linked immunosorbent assay. Cell proliferation was measured by Cell Counting Package-Eight assay. Additional, mRNA and protein expressions had been assessed by quantitative polymerase chain response and western blotting, respectively. Pulling down of FGF receptor 4 (FGFR4) by transfection with siRNA was used to substantiate the function of FGF19/FGFR4 signaling.
Outcomes: Utilizing the human HSC cell line LX-2, we screened a number of pure merchandise and located that bioactive compounds remoted from Salvia miltiorrhiza, notably salvianolic acid B, strongly upregulated FGF19 secretion by LX-2 cells. We additional confirmed that salvianolic acid B inhibited lipopolysaccharide (LPS)-induced HSC proliferation and activation. LPS remedy might also cut back the mRNA and protein ranges of FGF19 and its receptor FGFR4. Salvianolic acid B remedy restored the impaired expressions of FGF19 and FGFR4. Lastly, FGFR4 knockdown abolished the antifibrotic results of salvianolic acid B within the LPS-induced HSC activation mannequin.
Conclusions: Salvianolic acid B prevented LPS-induced HSC proliferation and activation by enhancing antifibrotic FGF19/FGFR4 signaling.

Glutaredoxin deficiency promotes activation of the reworking development issue beta pathway in airway epithelial cells, in affiliation with fibrotic airway transforming

S-glutathionylation of reactive protein cysteines is a post-translational occasion that performs a important function in transducing indicators from oxidants into organic responses. S-glutathionylation might be reversed by the deglutathionylating enzyme glutaredoxin (GLRX). Now we have beforehand demonstrated that ablation of Glrx sensitizes mice to the event of parenchymal lung fibrosis(1). It stays unclear whether or not GLRX additionally controls airway fibrosis, a scientific function related to bronchial asthma and continual obstructive pulmonary illness, and whether or not GLRX controls the biology of airway epithelial cells, which have been implicated within the pathophysiology of those ailments.
Within the current examine we utilized a home mud mite (HDM) mannequin of allergic airway illness in wild sort (WT) and Glrx-/- mice on a C57BL/6 background susceptible to develop airway fibrosis, and tracheal basal stem cells derived from WT mice, international Glrx-/- mice, or bi-transgenic mice permitting conditional ablation of the Glrx gene. Herein we present that absence of Glrx led to enhanced HDM-induced collagen deposition, elevated ranges of reworking development issue beta 1 (TGFB1) within the bronchoalveolar lavage, and resulted in will increase in airway hyperresponsiveness. Airway epithelial cells remoted from Glrx-/- mice or following conditional ablation of Glrx confirmed spontaneous will increase in secretion of TGFB1. Glrx-/- basal cells additionally confirmed spontaneous TGFB pathway activation, in affiliation with elevated expression of mesenchymal genes, together with collagen 1a1 and fibronectin. Total, these findings counsel that GLRX regulates airway fibrosis through a mechanism(s) that contain the plasticity of basal cells, the stem cells of the airways.
The outbreak of the 2019 coronavirus illness (named, COVID‑19), brought on by the novel SARS‑CoV‑2 virus, represents a worldwide extreme risk to public well being. It’s of the utmost significance to characterize the immune responses towards the SARS‑CoV‑2 and the mechanisms of hyperinflammation, to be able to design higher therapeutic methods for COVID‑19. Within the current examine, a transcriptomic evaluation was carried out to profile the immune signatures in lung and the bronchoalveolar lavage fluid samples from COVID‑19 sufferers and controls. Our information concordantly revealed elevated humoral responses to an infection. The elucidation of the host responses to SARS‑CoV‑2 an infection could additional enhance our understanding of COVID‑19 pathogenesis and counsel higher therapeutic methods.
 Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling

Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling

Analysis of Bcell intracellular signaling by monitoring the PI3K-Akt axis in sufferers with frequent variable immunodeficiency and activated phosphoinositide 3-kinase delta syndrome

Background: Major antibody deficiencies (PADs) are characterised by hypogammaglobulinemia and impaired B-cell differentiation. Sufferers with frequent variable immunodeficiency (CVID) current extreme reductions in not less than 2 serum immunoglobulins and impaired terminal differentiation of B cells. Most sufferers with CVID don’t seem to current monogenic defects. Activated phosphoinositide 3-kinase delta syndrome (APDS), brought on by gain-of-function mutations within the PIK3CD gene (p110δ), can current in sufferers with a CVID-like phenotype. Reminiscence B-cell differentiation requires the orchestrated activation of quite a few intracellular signaling pathways, which promote transcriptional packages required for long-term B-cell survival. The goal of this examine was to develop a circulation cytometry assay to hint the PI3K-Akt-mTOR pathway, a important part of B-cell homeostasis, and analyze its standing in PADs.
Strategies: We analyzed the intracellular expression of Akt and S6 by circulation cytometry and their phosphorylation standing in each baseline circumstances and upon B-cell receptor activation with anti-IgM in numerous main B-cell subsets of sufferers with CVID and APDS.
Outcomes: B cells from CVID sufferers confirmed decreased phosphorylation in Akt and S6 proteins after anti-IgM stimulation. Constitutive excessive baseline B-cell ranges of Akt and S6 phosphorylation in a affected person with APDS had been decreased as soon as m-TOR inhibition remedy was initiated.

Immunoglobulin Kappa (Igk) Antibody

20-abx176922
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug

Immunoglobulin Kappa (Igk) Antibody

20-abx176923
  • EUR 453.00
  • EUR 133.00
  • EUR 1302.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Immunoglobulin G1 Kappa (IgG1 Kappa) Protein

abx670165-1mg 1 mg
EUR 467

Human Immunoglobulin G2 Kappa (IgG2 Kappa) Protein

abx670166-1mg 1 mg
EUR 523

Mouse Immunoglobulin G1 Kappa (IgG1 Kappa) Protein

abx670291-1mg 1 mg
EUR 634

Mouse Immunoglobulin G2a Kappa (IgG2a Kappa) Protein

abx670292-1mg 1 mg
EUR 634

Mouse Immunoglobulin G2b Kappa (IgG2b Kappa) Protein

abx670293-1mg 1 mg
EUR 634

Mouse Immunoglobulin M Kappa (IgM Kappa) Protein

abx670294-1mg 1 mg
EUR 634

Mouse Immunoglobulin E Kappa (IgE Kappa) Protein

abx670299-05mg 0.5 mg
EUR 606

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

OVA Conjugated Immunoglobulin Kappa (Igk)

4-CPD038Hu21
  • EUR 410.02
  • EUR 212.00
  • EUR 1262.56
  • EUR 487.52
  • EUR 875.04
  • EUR 337.00
  • EUR 3006.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Immunoglobulin Kappa expressed in: Protein conjugation

OVA Conjugated Immunoglobulin Kappa (Igk)

4-CPD038Mu21
  • EUR 458.40
  • EUR 226.00
  • EUR 1444.00
  • EUR 548.00
  • EUR 996.00
  • EUR 370.00
  • EUR 3460.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Immunoglobulin Kappa expressed in: chemical synthesis

Immunoglobulin Kappa (Igk) Antibody Pair

20-abx370695
  • EUR 1790.00
  • EUR 1135.00
  • 10 × 96 tests
  • 5 × 96 tests

Immunoglobulin Kappa (Igk) Antibody (FITC)

20-abx270388
  • EUR 565.00
  • EUR 662.00
  • EUR 314.00
  • EUR 1024.00
  • EUR 411.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Immunoglobulin Kappa (Igk) Antibody (APC)

20-abx270620
  • EUR 759.00
  • EUR 899.00
  • EUR 384.00
  • EUR 1455.00
  • EUR 537.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Immunoglobulin Kappa (Igk) Antibody (PE)

20-abx270852
  • EUR 662.00
  • EUR 773.00
  • EUR 356.00
  • EUR 1233.00
  • EUR 467.00
  • 100 tests
  • 200 tests
  • 25 tests
  • 500 tests
  • 50 tests

Immunoglobulin Kappa (Igk) Antibody (PE)

20-abx274585
  • EUR 495.00
  • EUR 258.00
  • EUR 1455.00
  • EUR 676.00
  • EUR 398.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Immunoglobulin Kappa (Igk) Antibody (APC)

20-abx274586
  • EUR 565.00
  • EUR 272.00
  • EUR 1776.00
  • EUR 815.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Recombination Signal Binding Protein For Immunoglobulin Kappa J Region (RBPJ) Antibody

abx122950-100ug 100 ug
EUR 391

Recombination Signal Binding Protein For Immunoglobulin Kappa J Region (RBPJ) Antibody

abx237195-100ug 100 ug
EUR 509

Recombination Signal Binding Protein For Immunoglobulin Kappa J Region (RBPJ) Antibody

abx237196-100ug 100 ug
EUR 551

Recombination Signal Binding Protein For Immunoglobulin Kappa J Region Like (RBPJL) Antibody

abx237197-100ug 100 ug
EUR 551

Human Immunoglobulin Kappa (Igk) ELISA Kit

SED038Hu-10x96wellstestplate 10x96-wells test plate
EUR 4731.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immunoglobulin Kappa (Igk) in serum, plasma and other biological fluids.

Human Immunoglobulin Kappa (Igk) ELISA Kit

SED038Hu-1x48wellstestplate 1x48-wells test plate
EUR 477.3
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immunoglobulin Kappa (Igk) in serum, plasma and other biological fluids.

Human Immunoglobulin Kappa (Igk) ELISA Kit

SED038Hu-1x96wellstestplate 1x96-wells test plate
EUR 639
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immunoglobulin Kappa (Igk) in serum, plasma and other biological fluids.

Human Immunoglobulin Kappa (Igk) ELISA Kit

SED038Hu-5x96wellstestplate 5x96-wells test plate
EUR 2575.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immunoglobulin Kappa (Igk) in serum, plasma and other biological fluids.

Human Immunoglobulin Kappa (Igk) ELISA Kit

4-SED038Hu
  • EUR 4782.00
  • EUR 2526.00
  • EUR 640.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Immunoglobulin Kappa (Igk) in samples from Serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

SED038Mu-10x96wellstestplate 10x96-wells test plate
EUR 4862.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immunoglobulin Kappa (Igk) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

SED038Mu-1x48wellstestplate 1x48-wells test plate
EUR 488.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immunoglobulin Kappa (Igk) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

SED038Mu-1x96wellstestplate 1x96-wells test plate
EUR 654.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immunoglobulin Kappa (Igk) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

SED038Mu-5x96wellstestplate 5x96-wells test plate
EUR 2644.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immunoglobulin Kappa (Igk) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

4-SED038Mu
  • EUR 4913.00
  • EUR 2595.00
  • EUR 655.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Immunoglobulin Kappa (Igk) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Immunoglobulin Kappa (Igk) Polyclonal Antibody (Mouse)

4-PAD038Mu08
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin Kappa (Igk)

Mouse Immunoglobulin M Kappa (IgM) Antibody

20511-05011 150 ug
EUR 217

Human Immunoglobulin Kappa (Igk) CLIA Kit

20-abx494060
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Immunoglobulin Kappa (Igk) Protein (OVA)

20-abx651861
  • EUR 578.00
  • EUR 258.00
  • EUR 1706.00
  • EUR 676.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Immunoglobulin Kappa (Igk) CLIA Kit

20-abx496452
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Immunoglobulin Kappa (Igk) ELISA Kit

20-abx156942
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Immunoglobulin Kappa (Igk) ELISA Kit

20-abx258908
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Immunoglobulin Kappa (Igk) Antibody (APC/Cy7)

20-abx274584
  • EUR 968.00
  • EUR 411.00
  • EUR 3376.00
  • EUR 1455.00
  • EUR 732.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Immunoglobulin Kappa(Igk)ELISA Kit

QY-E02169 96T
EUR 361

Anti-Kappa Light Chain Antibody Clone SPM508, Unconjugated-100ug

3514-MSM1X-P1 100ug
EUR 428

Anti-Kappa Light Chain Antibody Clone HP6053, Unconjugated-100ug

3514-MSM4-P1 100ug
EUR 428

Anti-Kappa Light Chain Antibody Clone KLC709, Unconjugated-100ug

3514-MSM6-P1 100ug
EUR 428

Anti-Kappa Light Chain Antibody Clone KLC1278, Unconjugated-100ug

3514-MSM8-P1 100ug
EUR 428

Recombinant Human Glutathione S-transferase kappa 1 Protein, GST, E.coli-100ug

QP6125-ec-100ug 100ug
EUR 426

Anti-Kappa antibody

STJ160049 1 mL C
EUR 235
Description: Anti-Kappa recognizes surface immunoglobulin on normal and neoplastic B-cells, and has been indicated as a potential aid in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas, where the expression of a single light chain class is restricted. The determination of light chain ratio is critical in evaluating B-cell neoplasms, as the majority of B-cell lymphomas express either kappa or lambda light chains, while a mixture of kappa and lambda is characteristic of reactive proliferations. In paraffin-embedded tissue, Anti-Kappa displays strong staining of kappa-positive plasma cells, as well as cells that have absorbed exogenous immunoglobulins.

Anti-Kappa antibody

STJ180139 0.1 ml
EUR 212

Anti-Kappa antibody

STJ180388 0.1 ml
EUR 212

Anti-CD314 Antibody [CX5], Unconjugated-100ug

QAB100-100ug 100ug
EUR 182

Anti-CD4 Antibody [OKT4], Unconjugated-100ug

QAB11-100ug 100ug
EUR 123

Anti-CD8a Antibody [Hit8a], Unconjugated-100ug

QAB20-100ug 100ug
EUR 149

Anti-CD11c Antibody [N418], Unconjugated-100ug

QAB23-100ug 100ug
EUR 157

Anti-CD11c Antibody [3.9], Unconjugated-100ug

QAB24-100ug 100ug
EUR 141

Anti-CD11b Antibody [ICRF44], Unconjugated-100ug

QAB25-100ug 100ug
EUR 141

Anti-CD19 Antibody [1D3], Unconjugated-100ug

QAB28-100ug 100ug
EUR 141

Anti-CD3 Antibody [17A2], Unconjugated-100ug

QAB3-100ug 100ug
EUR 141

Anti-CD25 Antibody [PC61.5], Unconjugated-100ug

QAB34-100ug 100ug
EUR 123

Anti-CD25 Antibody [BC96], Unconjugated-100ug

QAB35-100ug 100ug
EUR 141

Anti-CD27 Antibody [O323], Unconjugated-100ug

QAB36-100ug 100ug
EUR 141

Anti-CD28 Antibody [CD28.2], Unconjugated-100ug

QAB37-100ug 100ug
EUR 141

Anti-CD45.1 Antibody [A20], Unconjugated-100ug

QAB42-100ug 100ug
EUR 157

Anti-CD45.2 Antibody [104], Unconjugated-100ug

QAB43-100ug 100ug
EUR 141

Anti-CD45RO Antibody [UCHL1], Unconjugated-100ug

QAB44-100ug 100ug
EUR 141

Anti-CD45RA Antibody [HI100], Unconjugated-100ug

QAB45-100ug 100ug
EUR 141

Anti-CD45 Antibody [HI30], Unconjugated-100ug

QAB46-100ug 100ug
EUR 141

Anti-CD3 Antibody [OKT3], Unconjugated-100ug

QAB5-100ug 100ug
EUR 149

Anti-CD3 Antibody [UCHT1], Unconjugated-100ug

QAB6-100ug 100ug
EUR 141

Anti-CD8a Antibody [2.43], Unconjugated-100ug

QAB61-100ug 100ug
EUR 149

Anti-CD3 Antibody [Hit3a], Unconjugated-100ug

QAB7-100ug 100ug
EUR 141

Anti-KLRG1 Antibody [2F1], Unconjugated-100ug

QAB74-100ug 100ug
EUR 141

Anti-CD161 Antibody [PK136], Unconjugated-100ug

QAB78-100ug 100ug
EUR 141

Anti-CD4 Antibody [GK1.5], Unconjugated-100ug

QAB8-100ug 100ug
EUR 123

Anti-CD32 Antibody [2.4G2], Unconjugated-100ug

QAB87-100ug 100ug
EUR 141

Anti-CD28 Antibody [37.51], Unconjugated-100ug

QAB99-100ug 100ug
EUR 149

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Anti-Kappa Light Chain Antibody Clone TB28-2, Unconjugated-100ug

3514-MSM3-P1 100ug
EUR 428

Anti-Kappa Light Chain Antibody Clone HP6053 + L1C1, Unconjugated-100ug

3514-MSM5-P1 100ug
EUR 428

Anti-Kappa Light Chain Antibody Clone Kap-56, Unconjugated-100ug

3514-MSM7-P1 100ug
EUR 428

Recombinant Human Immunoglobulin iota chain Protein, His-SUMO, E.coli-100ug

QP6882-ec-100ug 100ug
EUR 408

Immunoglobulin Kappa (Igk) Polyclonal Antibody (Mouse), APC

4-PAD038Mu08-APC
  • EUR 351.00
  • EUR 3365.00
  • EUR 935.00
  • EUR 449.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin Kappa (Igk). This antibody is labeled with APC.

Immunoglobulin Kappa (Igk) Polyclonal Antibody (Mouse), Cy3

4-PAD038Mu08-Cy3
  • EUR 427.00
  • EUR 4445.00
  • EUR 1205.00
  • EUR 557.00
  • EUR 254.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin Kappa (Igk). This antibody is labeled with Cy3.

Immunoglobulin Kappa (Igk) Polyclonal Antibody (Mouse), PE

4-PAD038Mu08-PE
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin Kappa (Igk). This antibody is labeled with PE.

Immunoglobulin Kappa (Igk) Polyclonal Antibody (Mouse), Biotinylated

4-PAD038Mu08-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin Kappa (Igk). This antibody is labeled with Biotin.

Immunoglobulin Kappa (Igk) Polyclonal Antibody (Mouse), FITC

4-PAD038Mu08-FITC
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin Kappa (Igk). This antibody is labeled with FITC.

Immunoglobulin Kappa (Igk) Polyclonal Antibody (Mouse), HRP

4-PAD038Mu08-HRP
  • EUR 321.00
  • EUR 2933.00
  • EUR 827.00
  • EUR 405.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Immunoglobulin Kappa (Igk). This antibody is labeled with HRP.

ELISA kit for Human Igk (Immunoglobulin Kappa)

ELK5262 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Immunoglobulin Kappa from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse Igk (Immunoglobulin Kappa)

ELK7759 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Immunoglobulin Kappa from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Human kappa immunoglobulin light chain ELISA Kit

ELA-E0644h 96 Tests
EUR 824

Monkey Kappa immunoglobulin light chain ELISA kit

E09K0067-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Kappa immunoglobulin light chain ELISA kit

E09K0067-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Kappa immunoglobulin light chain ELISA kit

E09K0067-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Kappa immunoglobulin light chain ELISA kit

E08K0067-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Canine Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Kappa immunoglobulin light chain ELISA kit

E08K0067-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Canine Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Kappa immunoglobulin light chain ELISA kit

E08K0067-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Canine Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Kappa immunoglobulin light chain ELISA kit

E01K0067-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Kappa immunoglobulin light chain ELISA kit

E01K0067-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Kappa immunoglobulin light chain ELISA kit

E01K0067-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Kappa immunoglobulin light chain ELISA kit

E03K0067-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Kappa immunoglobulin light chain ELISA kit

E03K0067-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Kappa immunoglobulin light chain ELISA kit

E03K0067-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Kappa immunoglobulin light chain ELISA kit

E02K0067-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Kappa immunoglobulin light chain ELISA kit

E02K0067-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Kappa immunoglobulin light chain ELISA kit

E02K0067-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Kappa immunoglobulin light chain ELISA kit

E07K0067-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Kappa immunoglobulin light chain ELISA kit

E07K0067-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Kappa immunoglobulin light chain ELISA kit

E07K0067-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Kappa immunoglobulin light chain ELISA kit

E06K0067-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Goat Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Kappa immunoglobulin light chain ELISA kit

E06K0067-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Goat Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Kappa immunoglobulin light chain ELISA kit

E06K0067-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Goat Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Kappa immunoglobulin light chain ELISA kit

E04K0067-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Kappa immunoglobulin light chain ELISA kit

E04K0067-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Kappa immunoglobulin light chain ELISA kit

E04K0067-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit Kappa immunoglobulin light chain in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Recombinant Human Immunoglobulin lambda-like polypeptide 5 Protein, His, Yeast-100ug

QP9714-ye-100ug 100ug
EUR 480

Anti-c-Myc Antibody [9E10], Unconjugated-100ug

QAB102-100ug 100ug
EUR 216

Anti-CD4 Antibody [RPA-T4], Unconjugated-100ug

QAB12-100ug 100ug
EUR 123

Anti-CD8a Antibody [53-6.7], Unconjugated-100ug

QAB16-100ug 100ug
EUR 131

Anti-CD8a Antibody [RPA-T8], Unconjugated-100ug

QAB19-100ug 100ug
EUR 149

Anti-CD3e Antibody [145-2C11], Unconjugated-100ug

QAB2-100ug 100ug
EUR 123

Anti-CD45 Antibody [30-F11], Unconjugated-100ug

QAB40-100ug 100ug
EUR 149

Anti-CD80 Antibody [16-10A1], Unconjugated-100ug

QAB50-100ug 100ug
EUR 182

Anti-CD86 Antibody [GL-1], Unconjugated-100ug

QAB51-100ug 100ug
EUR 157

Anti-CD161 Antibody [HP-3G10], Unconjugated-100ug

QAB60-100ug 100ug
EUR 157

Anti-IL-4 Antibody [11B11], Unconjugated-100ug

QAB81-100ug 100ug
EUR 149

Anti-FCER1A Antibody [MAR-1], Unconjugated-100ug

QAB91-100ug 100ug
EUR 182

Kappa Light Chain MonoSpecific Antibody, Unconjugated-100ug

3514-MSM11-P1 100ug
EUR 428

Kappa Casein (CSN3) Antibody

abx232019-100ug 100 ug
EUR 481

Anti-CD11c Antibody [N418], APC-100ug

QAB23-APC-100ug 100ug
EUR 242

Anti-CD11c Antibody [N418], Biotin-100ug

QAB23-B-100ug 100ug
EUR 182

Anti-CD11c Antibody [N418], FITC-100ug

QAB23-F-100ug 100ug
EUR 157

Anti-CD11c Antibody [N418], PE-100ug

QAB23-PE-100ug 100ug
EUR 225
Conclusions: Intracellular circulation cytometry might be routinely employed to discover alterations within the PI3K-Akt-mTOR pathway in B cells from sufferers with PADs. AKT and S6 phosphorylation ranges are informative biomarkers that may very well be employed as mTOR inhibitors for monitoring therapies focusing on this pathway.