Tag: exosomes and ra

December 10, 2020

Expanded and activated allogeneic NK cells are cytotoxic against B-chronic lymphocytic leukemia (B-CLL) cells with sporadic cases of resistance

Adoptive switch of allogeneic pure killer (NK) cells is changing into a reputable immunotherapy for hematological malignancies. Within the current work, utilizing an optimized enlargement/activation protocol of human NK cells, we generate expanded NK cells (eNK) with elevated expression of CD56 and NKp44, whereas sustaining that of CD16. These eNK cells exerted important cytotoxicity towards cells from 34 B-CLL sufferers, with only one pattern exhibiting […]